Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

MAKEITSIMPLE

Financiado

Cerrado

Make it simple towards a new era for organic synthesis

Organic synthesis has undeniably made tremendous progress over the past two centuries. Nevertheless, our ability to efficiently synthesise molecules is mostly limited to targets of low structural complexity. Traditional synthetic... ver más

30/09/2016

UNIVERSITY OF MANC...

1M€

Presupuesto del proyecto: 1M€

Líder del proyecto

THE UNIVERSITY OF MANCHESTER No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 2 Participantes

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2016-09-30 No tenemos la información de la convocatoria

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

2 Participantes

UNIVERSITY OF MANCHESTER

0.00€ | Lider

QMUL

N.D. | Participante

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

distalC-Hfun Transient directing group for catalytic distal C H functiona... 225K€ Cerrado

CTQ2016-77047-P FUNCIONALIZACION CATALITICA DE ENLACES C-H "INERTES": NUEVAS... 85K€ Cerrado

ENAFUNTRAMECAT Remote Enantioselective Functionalization of C H bonds in Sa... 222K€ Cerrado

CHACTSCS New metal catalised C H bond activation strategies for chemi... 129K€ Cerrado

metaC-Hfunct CO2 as a traceless directing group for catalytic meta C H ol... 183K€ Cerrado

IJCI-2017-31450 Transition metal-catalyzed assembly of elaborated heterocycl... 64K€ Cerrado

Líder del proyecto

THE UNIVERSITY OF MANCHESTER No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 1M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Organic synthesis has undeniably made tremendous progress over the past two centuries. Nevertheless, our ability to efficiently synthesise molecules is mostly limited to targets of low structural complexity. Traditional synthetic strategies require the presence of reactive functional groups that are used as handles for further functionalisation. This requirement is one of the factors dramatically enhancing the difficulty of syntheses. The last two decades have seen the emergence of a more straightforward alternative: the direct functionalisation of C-H bonds. Through this strategy the typically inert C-H bonds, ubiquitous in organic molecules, can be activated by transition metal catalysts and subsequently functionalised. This approach has allowed us to dream of a future where any organic molecule could be synthesised in a direct manner by simply replacing the C-H bonds of a substrate with the required functionalities, as if building a ball-and-stick molecular model with our hands. The development of a full set of C-H functionalisation methodologies will impact on all applied areas, such as the synthesis of pharmaceuticals, agrochemicals, and new materials. Furthermore, their atom efficiency and low waste generation ensures a privileged position among the green chemistry methods. For this strategy to succeed, numerous challenges are still to be overcome. In this research proposal we aim at addressing one of them: the C-H functionalisation of aromatic compounds. We will build up a toolkit of complementary methodologies to functionalise aromatic C-H bonds under mild conditions (energy efficient), with broad functional group tolerance (general), and with absolute control of the regioselectivity. By the end of the five years we aim to have developed a robust general methodology allowing the coupling of any two arenes via double C-H bond activation.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores