LUCERO-BIO
Financiado
LUCERO BIO: Smart Optofluidic Isolation of Spheroids for Early-Stage Drug Discov...
Personalised medicine has become a key focus for the pharmaceutical industry as it can address global health challenges, such as
strong variations of drug efficacy and toxicity linked to different patient subgroups. A major obstac...
Personalised medicine has become a key focus for the pharmaceutical industry as it can address global health challenges, such as
strong variations of drug efficacy and toxicity linked to different patient subgroups. A major obstacle that pharmaceutical companies still face is the lack of enabling technologies to predict the effects of drug candidates in patients before entering clinical trials. In preclinical drug screening procedures, pharmaceutical companies demand that the technologies be selective in terms of detection and isolation of patient-derived 3D cell cultures while being scalable for high-throughput drug screening. Lucero fills this need by providing a novel cell-handling platform that combines microfluidics, optical tweezers and artificial intelligence. During our ERC PoC project, we developed an integrated benchtop device for in-vitro handling of single 3D cell cultures, in particular mini spheroids. Lucero will build on this achievement by expanding our prototype’s functionalities and adapting its design to automatically detect spheroid viability and fully automate their isolation, to match the drug screening workflow. By thoroughly testing the prototype’s performance and compatibility with our large European pharmaceutical partner on-site, we will mature our prototype to technological readiness level (TRL) 6. Based on their feedback we will increase our commercial readiness level (CRL) 6 and will be ready for the next acceleration phase.
The intended result of this proposal is to introduce Lucero’s 3D cell-handling platform as an enabling tool for pharmaceutical
companies to develop more effective near-patient treatments at a lower cost, as well as to establish Europe as a leader in precision healthcare.
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Duración del proyecto: 38 meses
Fecha Inicio: 2022-10-26
Fecha Fin: 2025-12-31
Fecha Fin: 2025-12-31
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-10-26
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
HORIZON-EIC-2021-TRANSITIONOPEN-01:
EIC Transition Open 2021
Cerrada
hace 3 años
Presupuesto
El presupuesto total del proyecto asciende a
1M€
Líder del proyecto
Lucero AB
No se ha especificado una descripción o un objeto social para esta compañía.
