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LongTREC

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Long TREC The Long Reads Transcriptomics European Consortium. The next generati...

Long TREC The Long Reads Transcriptomics European Consortium. The next generation transcriptome biology revealed by single molecule sequencing technologies Thrid-generation, single-molecule long-read sequencing technologies such as Nanopore and Pacbio are revolutionizing transcriptome research and are expected to outcompete short-reads sequencing for gene expression studies. However,... see more

30/09/2026

CSIC

3M€

Project Budget: 3M€

Project leader

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGA... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 2-3 | 552M€

PARTICIPATION DEPralty Sin fecha límite de participación.

Ver 28 Participantes

Financing granted El organismo HORIZON EUROPE notifico la concesión del proyecto The day 2022-07-14

HORIZON-MSCA-2021-DN-01-01: MSCA Doctoral Networks 2021 ExpectedOutcome:

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Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

28 Participantes

CSIC

251.97K€ | Leader

IIT

259.44K€ | participant

THE UNIVERSITY OF NOTTINGHAM

N.D. | participant

UNIVERSITE PARISSACLAY

N.D. | participant

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Project duration: 50 months Date Start: 2022-07-14
End date: 2026-09-30

Project leader

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGA... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 2-3 | 552M€

Project Budget 3M€

participation deadline Sin fecha límite de participación.

Project description Thrid-generation, single-molecule long-read sequencing technologies such as Nanopore and Pacbio are revolutionizing transcriptome research and are expected to outcompete short-reads sequencing for gene expression studies. However, technical and bioinformatics challenges exist to the realization of this full potential. In this project, we will train a team of excellent Doctoral Candidates to become the European and world leaders in the field of long reads transcriptome sequencing (lrRNA-seq). The team will address three fundamental aspects of current barriers to the progress that these technologies face. a) Obtaining high-quality sequencing and preprocessed data from improved library preparation protocols and bioinformatics preprocessing methods, b) Establishment of benchmarked analysis pipelines for the application of these approaches to genome annotation and isoform usage analysis both in bulk and single-cell samples, and c) Extension of long reads to multi-omics applications for the study of regulatory biology. Additionally, DC will follow an intensive and comprehensive training program composed of scientific and soft skills training, including activities related to pressing societal challenges such as climate change, diversity and inclusion, and the ethics of science. Students will complement their education through secondments in top European laboratories and Companies as well as through exposure to a network of worldwide experts in the field of RNA research.

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