Innovating Works

Lakhesys

Financiado
Lakhesys building the machine to make the medicines of tomorrow
Chimeric Antigen Receptor T-cell therapies (‘CAR-T’) are ushering in an incredibly exciting era of using a patient’s own cells to cure their cancer. The prospect of using a patient’s own cells to cure their disease is theoretica... Chimeric Antigen Receptor T-cell therapies (‘CAR-T’) are ushering in an incredibly exciting era of using a patient’s own cells to cure their cancer. The prospect of using a patient’s own cells to cure their disease is theoretically limitless. However, with all of this excitement comes a shadow. The cost of these life-saving treatments is currently so prohibitive that it threatens to put extreme cost-pressure on healthcare providers globally in the years ahead. Astraveus has developed a highly innovative microfluidic chip that can fundamentally change the CAR-T industry. This chip answers the need to lower production cost (by ~70%), improve treatment quality and allow upscaling of treatment volumes to the required levels. Astraveus has also developed equipment to optimize the use of these microfluidic chips. They have incorporated these technologies into a working prototype of an instrument called ‘Lakhesys’. This instrument allows for automated, standalone, end-to-end production of a CAR-T therapy. The design, fabrication and validation of the microfluidic innovation is a real breakthrough in the ability to cheaply and accurately produce these treatments. The further step of incorporating these chips into a prototype system demonstrates the huge potential for automating CAR-T production. This phase-2 project will upgrade the supporting modules to turn this working prototype into a launch-ready product. It will also support the validation and industrialisation steps to bring this innovation to market. The industry is dominated by players in the USA and China (72% of CAR-T institutions are based in these two countries). Astraveus has invented something incredibly unique and a complete step-change versus anything seen on the market. As such, we present an opportunity to support the creation of a homegrown EU business that can challenge the status quo and, more importantly, put these life-saving therapies in the hands of all patients who need them. ver más
28/02/2023
ASTRAVEUS
3M€
Duración del proyecto: 48 meses Fecha Inicio: 2019-02-28
Fecha Fin: 2023-02-28

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2023-02-28
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
EIC-SMEInst-2018-2020: SME instrument
Cerrada hace 6 años
Presupuesto El presupuesto total del proyecto asciende a 3M€
Líder del proyecto
ASTRAVEUS SAS No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5