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KINETICfinder

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KINETICfinder A disruptive method to determine kinetic profiles in drug discove...

KINETICfinder A disruptive method to determine kinetic profiles in drug discoveries Bringing Bringing a new drug to the market costs 2,600 M€ and it takes 12 years. In addition, around 80% of drugs under research do not reach clinical trials (due to toxicity or lack of efficacy). ENZYMLOGIC was created with the a... see more

30/11/2019

ENZYMLOGIC

71K€

Project Budget: 71K€

Project leader

ENZYMLOGIC La investigación, diseño, desarrollo, fabricación, experimentación, simulación, explotación, importación, exportación y comercialización de...

TRL 4-5 | 653K€

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo H2020 notifico la concesión del proyecto The day 2019-11-30

EIC-SMEInst-2018-2020: SME instrument

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2 Participantes

ENZYMLOGIC

50.00K€ | Leader

PLASTICOS ESCANERO

336.95K€ | participant

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Project duration: 6 months Date Start: 2019-05-24
End date: 2019-11-30

Project leader

ENZYMLOGIC La investigación, diseño, desarrollo, fabricación, experimentación, simulación, explotación, importación, exportación y comercialización de...

TRL 4-5 | 653K€

Project Budget 71K€

participation deadline Sin fecha límite de participación.

Project description Bringing Bringing a new drug to the market costs 2,600 M€ and it takes 12 years. In addition, around 80% of drugs under research do not reach clinical trials (due to toxicity or lack of efficacy). ENZYMLOGIC was created with the aim of being a company in the niche of kinetic analysis. They have developed KINETICfinder: an experimental, robust, accurate and reproducible methodology that provides drug kinetic analyses in a massive way and at affordable cost, so it is possible to utilise it in early research stages, when thousands of drugs are involved. ENZYMLOGIC has been focused on providing auxiliar external analysis having pharmaceutical companies as customers. Nowadays, there are no comparable technologies capables of generating this amount of information with this level of processivity (number of drugs analysed at the same time). Currently, this analysis is extremely slow and costly, thus it is carried out in the final stages of the research, with just a small number of drugs. Otherwise, the number of different drugs they can analyse is 10 times higher and 10 times faster than other kinetic analysis (processivity). KINETICfinder can reduce the time and cost by 50% from the research phase of a new drug to the market phase. KINETICfinder already makes it possible to analyse 30 kinase targets (involved in cancer), and the next step is to work with GPCRs (neurodegenerative disorders, inflammation, pain, cardiovascular diseases and diabetes). 40% of the existing drugs are aimed at GPCRs. ENZYMLOGIC has obtained several prizes recognizing innovation and potential growth. The objective in phase I will be the validation of the use of KINETICfinder for working with GPCRs having as a base the previous work performed with kinases. To achieve this, the associated tasks shall be: validation of the method working with GPCRs having as a base the previous work performed with kinases, detailed market study & business plan elaboration and validation of commercialization strategy.

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