Joint Volumetric Reconstruction and Automated Analysis of the Fetal Heart from C...
Joint Volumetric Reconstruction and Automated Analysis of the Fetal Heart from Cardiovascular Magnetic Resonance Images
Recent advancements in cardiovascular magnetic resonance (CMR) have finally made possible static and dynamic in-vivo imaging of the fetal heart. This new capability has the potential to provide a fundamental new tool for structura...
ver más
¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video
Proyectos interesantes
SMHEART
Smart Cardiac Magnetic Resonance Delivering One-Click and Co...
1M€
Cerrado
HEARTMAPAS
Single Heart beat MApping of myocardial Performance Activat...
2M€
Cerrado
ACCELCMR
Accelerated myocardial perfusion metabolic and contractile...
181K€
Cerrado
MOUSIE
Multi Organ UltraSound based Inborn Evaluation
183K€
Cerrado
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
Recent advancements in cardiovascular magnetic resonance (CMR) have finally made possible static and dynamic in-vivo imaging of the fetal heart. This new capability has the potential to provide a fundamental new tool for structural and functional assessment of the fetal cardiovascular system, with groundbreaking clinical consequences. In fact, congenital heart diseases (CHDs) and intrauterine growth restriction (IUGR, which induces cardiovascular remodeling) are among the leading causes of infant mortality worldwide. Fetal CMR imaging may potentially allow more accurate diagnosis of these conditions, and thus improve postnatal outcomes thanks to better in-utero therapy administration, delivery and perinatal intervention planning. Unfortunately, fetal CMR is currently limited to the acquisition of a single slice in time, allowing only qualitative and operator-dependent evaluation of the fetal heart. The JUNO project aims at improving the present capabilities of fetal CMR by tackling its limitations with an image processing approach. The specific goals are (1) development of a method for super resolution volumetric reconstruction of the fetal heart, using image registration techniques applied to a set of single-slice acquisitions; (2) development of automated segmentation methods, based on deformable models and atlases, for the identification of structures such as ventricular contours and main vessels’ boundaries; (3) extraction of quantitative functional parameters (e.g. stroke volume and ejection fraction) from datasets acquired from healthy, CHDs- and IUGR-affected fetuses, to test the feasibility of objective detection of these conditions. By achieving these goals, JUNO will provide an innovative set of methods allowing for the first time quantitative, noninvasive, functional assessment of the fetal cardiovascular system, and thus address a long standing clinical need for such methodology.