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HealthAge

Financiado

Cerrado

Joint Training and Research Program on Lifespan Regulation Mechanisms in Health...

Joint Training and Research Program on Lifespan Regulation Mechanisms in Health and Disease Aging is an inexorable homeostatic failure of complex but largely unknown aetiology that leads to increased vulnerability to disease with enormous consequences on the quality of individual lives and the overall cost to society. Al... ver más

31/12/2023

FOUNDATION FOR RES...

4M€

Presupuesto del proyecto: 4M€

Líder del proyecto

IDRYMA TECHNOLOGIAS KAI EREVNAS No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 19 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2023-12-31

MSCA-ITN-2018: Innovative Training Networks

I+D

Cerrada hace 7 años

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

19 Participantes

FOUNDATION FOR RESEARCH AND...

486.04K€ | Lider

Amazentis

N.D. | Participante

EPFL

281.28K€ | Participante

UNIPD

261.50K€ | Participante

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Duración del proyecto: 64 meses Fecha Inicio: 2018-08-20
Fecha Fin: 2023-12-31

Líder del proyecto

IDRYMA TECHNOLOGIAS KAI EREVNAS No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 4M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Aging is an inexorable homeostatic failure of complex but largely unknown aetiology that leads to increased vulnerability to disease with enormous consequences on the quality of individual lives and the overall cost to society. Although, aging is driven by limitations in somatic maintenance, it is also subject to regulation by evolutionarily highly conserved molecular pathways. Indeed, macromolecular damage may drive the functional decline with aging; however, a battery of conserved, longevity assurance mechanisms may set the pace on how rapidly damage builds up and function is lost over time. Human efforts over the last centuries have succeeded in substantially lengthening lifespan, allowing aging to become a common feature of western societies. However, The discouraging complexity of the aging process, the noticeable lack of tools to study it, and a shortage of experimentally tractable model systems have made it significantly challenging to unravel the molecular basis of the processes that cause loss of bodily functions and degeneration of cells and tissues with advancing age. HealthAge was carefully designed to create a joint European program of excellence in training and research with a core intellectual focus on the functional role of Lifespan Regulation Mechanisms in Health and Disease. To tackle this, HealthAge combines top-level, state-of-the-art and interdisciplinary research skills that range from basic molecular mechanisms and ‘omics’ level understanding to translational research and clinical applications. This interdisciplinary strategy will allow us to gain functional insight into the fundamental mechanisms regulating longevity as well as to develop a series of rationalized intervention strategies aimed at counteracting age-related diseases.

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