Investigation of coupled bone and eggshell de mineralization during laying cycl...
Investigation of coupled bone and eggshell de mineralization during laying cycle of hens
Skeletal disorders in laying hens are a major concern for the food industry. It is well recognized that bone demineralization in laying hens is coupled to the daily mobilization of Ca for egg formation but the relation between bon...
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Información proyecto BonEggHens
Duración del proyecto: 38 meses
Fecha Inicio: 2022-06-08
Fecha Fin: 2025-08-31
Líder del proyecto
UNIVERSIDAD DE GRANADA
No se ha especificado una descripción o un objeto social para esta compañía.
Total investigadores5513
Presupuesto del proyecto
181K€
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
Skeletal disorders in laying hens are a major concern for the food industry. It is well recognized that bone demineralization in laying hens is coupled to the daily mobilization of Ca for egg formation but the relation between bone properties and eggshell quality is still unclear. A key point for understanding this coupled process is reveling the factors that influence bone dissolution since the unbalance between resorption and formation is what causes bone diseases such as osteoporosis and osteogenesis imperfecta. Notably, there is limited information on how the composition, structural organization and interaction between bone mineral phase and organic matrix in different bone types influence chicken bone dissolution and its mechanical properties. BonEggHens aims to perform a systematic study, from macro to nanoscopic scale, on a large array of bone and eggshell samples representative of the hen’s life cycle, to assess i) the effect of the mineral labile phase and the organic matrix on bone dissolution, ii) the relation between micro and nanoscopic characteristics of hen’s bones to bone quality parameters (e.g., bone density, mineral crystallinity) and iii) the correlation between bone structural and compositional changes and eggshell quality. The results of the proposed study will shed light on bone/eggshell (de)mineralization processes, which will help to find solutions for a more sustainable yet productive farming system for ovo-production. Moreover, the outcome of BonEggHens has potential implications for future biomineral investigation by cutting-edge microscopy tools and, most importantly, for the study of human bone diseases resembling those in chickens. Finally, the development of the proposal will be career-defining, contributing to the professional and personal growth of the experienced researcher and providing the necessary skills and competences to increase her competitiveness and attain a permanent position in the European scientific framework.