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RECODID

Financiado

Cerrado

Integrated human data repositories for infectious disease related international...

Integrated human data repositories for infectious disease related international cohorts to foster personalized medicine approaches to infectious disease research ReCoDID builds on existing infrastructures and partnerships to develop a sustainable model for the storage, curation, and analyses of the complex data sets collected by infectious disease (ID)-related cohorts. While ID cohorts col... ver más

31/12/2023

UKHD

9M€

Presupuesto del proyecto: 9M€

Líder del proyecto

UNIVERSITATSKLINIKUM HEIDELBERG No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 17 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2023-12-31

SC1-BHC-05-2018: International flagship collaboratio...

I+D

Cerrada hace 6 años

0% 88% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

17 Participantes

UKHD

1.45M€ | Lider

TECHNICAL UNIVERSITY OF DENM...

683.75K€ | Participante

ERASMUS MC

741.21K€ | Participante

AMU

451.55K€ | Participante

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Duración del proyecto: 61 meses Fecha Inicio: 2018-11-21
Fecha Fin: 2023-12-31

Líder del proyecto

UNIVERSITATSKLINIKUM HEIDELBERG No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 9M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto ReCoDID builds on existing infrastructures and partnerships to develop a sustainable model for the storage, curation, and analyses of the complex data sets collected by infectious disease (ID)-related cohorts. While ID cohorts collect both clinical-epidemiological (CE) and terabytes of OMICS data, storage and analysis of CE and high dimensional laboratory (HDL) data remains separate and developing the infrastructure for housing and analysing HDL data is not feasible for individual studies. In this project, we develop innovative approaches to the synthesis and analysis of CE&HDL data, and modify governance models for cloud-based repositories elaborated by and for scientists in high-income countries to meet the specific challenges of synthesizing CE&HDL data and sharing data across international cohorts and with the Open Science community. We develop data architecture and governance that link biobanks to data repositories to facilitate equitable use, collaborative, cross-domain analyses, and replicability. The team leverages partnerships with multicentre ID cohorts in the global South, and connects EU investments in OMICS infrastructures with Canadian expertise on pipeline and workflow development, biostatistical methods, and ethical and governance issues related to the establishment of repositories for CE&HDL data in resource-limited settings. Drawing from best practice and governance elaborated for similar initiatives, the repository will employ a federated model where a tiered permission system and cohort-specific hubs facilitate cohorts’ analysis of their own data, cross-cohort analyses, and connections with the open science community within a clearly elaborated legal, ethical, and equitable framework. The cloud-based platform will provide analytic tools and computational power to facilitate cross-domain, collaborative analyses that inform personalized medicine approaches to diagnostic, treatment, and vaccine development in ID-focused international cohorts.

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