Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

FarCatCH

Financiado

Innovative Strategies for Unprecedented Remote C H bond Functionalization by Cat...

Innovative Strategies for Unprecedented Remote C H bond Functionalization by Catalysis Over the last years, the landscape of the organic chemistry has been reshaped with impressive advances made in the transition metal-catalyzed carbon-hydrogen (C-H) bond functionalization field. Indeed, the functionalization of bui... ver más

31/12/2023

CNRS

1M€

Presupuesto del proyecto: 1M€

Líder del proyecto

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 2 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2023-12-31

ERC-2017-STG: ERC Starting Grant

I+D

Cerrada hace 8 años

0% 100% 100%

2 Participantes

CNRS

1.50M€ | Lider

INKOA SISTEMAS

194.85K€ | Participante

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

BES-2012-054798 CATALISIS ORGANOMETALICA: FUNCIONALIZACION DE ENLACES C-H 43K€ Cerrado

JCI-2011-09946 Organometallic Catalysis : C-H Bond Functionalization - Meta... 96K€ Cerrado

BES-2012-061338 STRATEGIES FOR THE CATALYTIC FUNCTIONALIZATION OF NON-ACTIVA... 43K€ Cerrado

BES-2012-057094 STRATEGIES FOR THE CATALYTIC FUNCTIONALIZATION OF NON-ACTIVA... 43K€ Cerrado

EIN2020-112430 FUNCIONALIZACION REMOTA DE ENLACES C-H MEDIANTE ESTRATEGIAS... 10K€ Cerrado

CTQ2016-77989-P PLATAFORMAS MODELO PARA LA COMPRESION MECANISTICA DE FUNCION... 163K€ Cerrado

Duración del proyecto: 75 meses Fecha Inicio: 2017-09-11
Fecha Fin: 2023-12-31

Líder del proyecto

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 1M€

Descripción del proyecto Over the last years, the landscape of the organic chemistry has been reshaped with impressive advances made in the transition metal-catalyzed carbon-hydrogen (C-H) bond functionalization field. Indeed, the functionalization of building blocks that do not display a reactive functional group but only a simple C-H bond is attractive as it avoids time-consuming and expensive prefunctionalization steps and limits the generation of waste. However, as energies required to break C-H bonds are similar, the differentiation between two C-H bonds and the selective functionalization of only one of them remain a key challenge. Therefore, the available approaches are still unsatisfactory due to important limitations: low reactivity, limited scopes and selectivity issues. In this proposal, a general approach to functionalize a CH bond located at a Far position (from a functional group) by Catalysis (FarCatCH) will be implemented with a special focus on underexplored transformations, affording important sulfur-and fluorine-containing compounds. Herein, I will develop new synthetic approaches for the remote functionalization of molecules based on i) a substrate-selectivity control and ii) the design of new catalysts using supramolecular tools. I will then iii) address a longstanding reactivity issue in organic synthesis: the trifluoromethylation of aliphatic compounds and apply the supramolecular catalysts for a remote enantioselective transformation. Designing a full set of tools as Swiss army knife for the selective functionalization at unconventional positions inaccessible so far, can considerably change the way organic molecules are made. These original technologies will offer new synthetic routes to access original sulfur- and fluorine-containing molecules, compounds of interest in drugs discovery, material sciences, pharmaceutical and agrochemical industry.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores