Improved Diagnosis and Management of Heart Disease by 4D Blood Flow Assessment
The primary purpose of the cardiovascular system is to drive, control and maintain blood flow to all parts of the body. Despite the primacy of flow, cardiac diagnostics still rely almost exclusively on tools focused on morphologic...
ver más
31/12/2017
LIU
1M€
Presupuesto del proyecto: 1M€
Líder del proyecto
Linköping University
No se ha especificado una descripción o un objeto social para esta compañía.
Fecha límite participación
Sin fecha límite de participación.
Financiación
concedida
El organismo FP7 notifico la concesión del proyecto
el día 2017-12-31
No tenemos la información de la convocatoria
0%
100%
100%
Características del participante
Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.
Información adicional privada
No hay información privada compartida para este proyecto. Habla con el coordinador.
¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video
Información proyecto HEART4FLOW
Líder del proyecto
Linköping University
No se ha especificado una descripción o un objeto social para esta compañía.
Presupuesto del proyecto
1M€
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
The primary purpose of the cardiovascular system is to drive, control and maintain blood flow to all parts of the body. Despite the primacy of flow, cardiac diagnostics still rely almost exclusively on tools focused on morphological assessment.
The objective of the HEART4FLOW project is to develop the next generation of methods for the non-invasive quantitative assessment of cardiac diseases and therapies by focusing on blood flow dynamics, with the goals of earlier and more accurate detection and improved management of cardiac diseases.
Recently, a novel moment framework for flow quantification using magnetic resonance imaging (MRI) has been presented which allows for simultaneous measurement of time-resolved, three-dimensional (time + 3D = 4D) blood flow velocity and turbulence intensity. In the HEART4FLOW project, this framework is extended and exploited for assessment of intracardiac blood flow dynamics. A user-friendly quantitative assessment approach is obtained for intracardiac blood flow energetics and wall interaction, as well as stenotic and regurgitant blood flow. Furthermore, the accuracy, measurement time, and robustness of 4D flow MRI acquisition are optimized, allowing its use in large clinical trails. Studying intracardiac blood flow dynamics in patients and healthy subjects at rest and under stress will improve our understanding of the roles of flow dynamics in both health and disease, leading to improved cardiac diagnostics, novel assessments of pharmaceutical, interventional, and surgical therapies, and promoting exploration of new avenues for management of cardiac disorders.