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NeuroSolve

Financiado

Cerrado

Implementation of superior treatment regimen and improved patient pathway for ne...

Implementation of superior treatment regimen and improved patient pathway for neurocysticercosis in Sub-Saharan Africa Neurocysticercosis (NCC) is a fatal zoonotic disease following ingestion of eggs of the pork tapeworm, Taenia solium. The eggs develop to larval forms (cysticerci) in various tissues, including those of the central nervous system,... ver más

30/04/2027

R-EVOWW

4M€

Presupuesto del proyecto: 4M€

Líder del proyecto

REVOLUTION WORLDWIDE SRL IMPRESA SOCIALE No se ha especificado una descripción o un objeto social para esta compañía.

Fecha límite participación Sin fecha límite de participación.

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Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-04-27

HORIZON-JU-GH-EDCTP3-2022-CALL1-01-04: Creating a sustainable clinical tri... Expected Outcome:This topic aims at supporting activities that are contributing to one or several of...

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Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

6 Participantes

R-EVOWW

715.25K€ | Lider

UGent

437.88K€ | Participante

UNIVERSITY OF DAR ES SALAAM

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Duración del proyecto: 48 meses Fecha Inicio: 2023-04-27
Fecha Fin: 2027-04-30

Líder del proyecto

REVOLUTION WORLDWIDE SRL IMPRESA SOCIALE No se ha especificado una descripción o un objeto social para esta compañía.

Presupuesto del proyecto 4M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Neurocysticercosis (NCC) is a fatal zoonotic disease following ingestion of eggs of the pork tapeworm, Taenia solium. The eggs develop to larval forms (cysticerci) in various tissues, including those of the central nervous system, leading to NCC, mainly characterized by epileptic seizures. NCC management guidelines have been published by the WHO, however, their uptake in national policies is very limited. In NeuroSolve, we will demonstrate and promote a methodological approach for conducting health research that leads to improved adoption into policy and clinical practise. We will validate the approach by investigating evaluation- and implementation of an antiparasitic combination treatment and a serological test. Two health innovations that can make a major positive contribution to NCC management. The proposed approach includes (1) strengthening of clinical and research capacity through training and mentoring of early career researchers, clinicians and frontline healthcare workers as well as upgrading infrastructure for surveillance and control, (2) demonstrating the improved pragmatic effectiveness of the combined treatment on quality of life (3) evaluating the potential impact of serological testing on the patient outcomes and the wider health system through a simulation study, (4) demonstrating the cost-effectiveness and cost-benefit of the proposed health technologies, (5) developing and validating an implementation strategy that addresses identified barriers for uptake using the robust implementation frameworks and 6) enhance research results uptake into national and international guidelines and health policy through engagement of relevant policy makers throughout the project period and beyond. If the intended impacts are reached, NeuroSolve will improve health outcomes of NCC patients, provide a blueprint for meaningful implementation research and demonstrate to policy makers how research can strengthen healthcare systems.

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