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Immune-Image

Financiado

Cerrado

Immune Image Specific Imaging of Immune Cell Dynamics Using Novel Tracer Strate...

Immune Image Specific Imaging of Immune Cell Dynamics Using Novel Tracer Strategies Immunotherapies have emerged as effective treatments for immune system-related diseases, such as cancer and inflammatory diseases. Although immunotherapeutics are effective not all patients benefit and side effects vary greatly. T... ver más

31/03/2026

STICHTING AMSTERDA...

27M€

Presupuesto del proyecto: 27M€

Líder del proyecto

STICHTING AMSTERDAM UMC No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 27 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2019-09-26

IMI2-2018-14-02: Non-invasive clinical molecular ima...

I+D

Cerrada hace 6 años

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

27 Participantes

STICHTING AMSTERDAM UMC

3.99M€ | Lider

ARITEX CADING

208.48K€ | Participante

BAYER AKTIENGESELLSCHAFT

254.53K€ | Participante

1.10M€ | Participante

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Duración del proyecto: 78 meses Fecha Inicio: 2019-09-26
Fecha Fin: 2026-03-31

Líder del proyecto

STICHTING AMSTERDAM UMC No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 27M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Immunotherapies have emerged as effective treatments for immune system-related diseases, such as cancer and inflammatory diseases. Although immunotherapeutics are effective not all patients benefit and side effects vary greatly. Thus, there is an unmet need for a personalized approach. Blood and tissue biomarkers have played only a modest role up until now in assessing immune status in vivo and we believe that non-invasive whole body imaging will make a significant contribution in the future. Although the field of imaging (PET, MRI, Optical Imaging) is flourishing, its application to patient immune status measurement and monitoring has barely been explored. Within Immune-Image we aim to develop new immunotracers for imaging specific immune cell subsets, develop quantitative imaging workflows, validate the immunotracers pre-clinically in relevant disease models, produce the tracers in a Good Manufacturing Practice (GMP)-compliant way, and conduct smart clinical trials, including with novel tracers. To this end, insights will be gained into the optimal use of drugs and a more efficient development of immunotherapeutics. Moreover, the success rate of immunotherapy development will be enhanced since our molecular imaging platform will provide novel insights into patient immune status, which will support drug development and treatment decisions. To achieve our goals, we have assembled an experienced international multi-disciplinary consortium composed of chemists, biologists, immunologists, physicists, pharmacists, information technologists, and medical specialists with diverse and essential backgrounds who will join forces to design, synthesise, evaluate and validate immunotracers and create sustainable molecular imaging techniques that can be broadly applied in the assessment of the immune status and immune modulation of patients. There will be input from patients and regulators in order to assure optimal design and execution of immunotracer clinical trials.

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