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iFermenter

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iFERMENTER CONVERSION OF FORESTRY SUGAR RESIDUAL STREAMS TO ANTIMICROBIAL PROT...

iFERMENTER CONVERSION OF FORESTRY SUGAR RESIDUAL STREAMS TO ANTIMICROBIAL PROTEINS BY INTELLIGENT FERMENTATION Plant dry matter, so-called lignocellulosic biomass, is the largest renewable biomass feedstock on Earth. Europe has over 14 mill tons of sugar residuals from biorefineries, which could be converted to profitable products and cont... ver más

31/07/2022

SINTEF

5M€

Presupuesto del proyecto: 5M€

Líder del proyecto

SINTEF AS No se ha especificado una descripción o un objeto social para esta compañía.

Fecha límite participación Sin fecha límite de participación.

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Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2022-07-31

BBI.2017.R4: Proteins and other bioactive ingred... Specific Challenge:Proteins and bioactive compounds, such as carotenoids, polyphenols, lipid compoun...

I+D

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Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Información adicional privada

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11 Participantes

SINTEF

995.03K€ | Lider

BIOPILOT PLANT BBEPP

438.47K€ | Participante

TECHNICAL UNIVERSITY OF DENM...

250.40K€ | Participante

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Duración del proyecto: 51 meses Fecha Inicio: 2018-04-24
Fecha Fin: 2022-07-31

Líder del proyecto

SINTEF AS No se ha especificado una descripción o un objeto social para esta compañía.

Presupuesto del proyecto 5M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Plant dry matter, so-called lignocellulosic biomass, is the largest renewable biomass feedstock on Earth. Europe has over 14 mill tons of sugar residuals from biorefineries, which could be converted to profitable products and contribute to a sustainable bioeconomy. Unfortunately, existing biorefineries struggle with technical issues and low profitability due to the lack of adequate fermentation processes. Therefore, these sugars are either incinerated to generate energy or at best converted to ethanol (€0.6 /kg) but not to higher value chemicals. Current concepts that aim to establish fermentation processes to convert residual sugar streams to high value products face challenges including inefficient sugar utilization by microorganisms and inhibitors in the residual streams, leading to low productivity and yields. Our project aims to recover high value compounds from sugar residuals, and to turn fermentation processes converting these residual to antimicrobials cost effective. We will recover the high value sugar galactose (€40-200 /kg) from residual streams as part of their treatment process. By genome editing technique, we will design cell factories that consume the remaining residuals and produce nisin (€50-150 /kg), an industrially important commercial food/feed preservative. Additionally, we will develop an affordable, online feedback add-on system that will allow to intelligently change residual mixture during fermentation of these cell factories to optimize production online during the process. In a 150 L industrial bioreactor, we will demonstrate that our add-on invention iFermenter - increases the yields of nisin by over 2 fold - increases the pediocin production by over 50% compared to what is possible today, - and reduce at least 20% in CO2 footprint with this process compared to existing solutions. Thus, iFermenter will render production of high value products with residual sugar stream highly efficient and cost-effective contributing to circular economy.

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