Pros-RODAM
Financiado
Hypertension Susceptibility in African Migrants Solving the puzzle through tran...
Hypertension Susceptibility in African Migrants Solving the puzzle through transcontinental prospective cohort study design
Hypertension is the most important modifiable cardiovascular risk factor. Migrants, especially people of Sub-Saharan African heritage, are extremely affected for reasons that are unclear. This project aims to understand the mechan...
Hypertension is the most important modifiable cardiovascular risk factor. Migrants, especially people of Sub-Saharan African heritage, are extremely affected for reasons that are unclear. This project aims to understand the mechanisms underlying the high risk of hypertension among African migrants by assessing the role of epigenetic modifications that result from rapid socio-environmental and behaviour change.
To achieve this, Agyemang and his team will establish an innovative transcontinental prospective cohort study of a homogeneous group of Sub-Saharan African migrants (Ghanaians) living in the Netherlands and non-migrant Ghanaians living in rural and urban Ghana. We will first examine and identify the key changes in modifiable environmental factors influencing the high risk of hypertension among migrants. Second, we will examine changes in epigenetic modifications and their effects on hypertension risk in migrants. Third, we will identify the key environmental factors that are driving the epigenetic changes. Last, we will estimate for the first time the individual and combined effect of environmental factors, and epigenetic modifications to the high risk of hypertension in migrants relative to non-migrant Europeans and Ghanaian counterparts living in Africa.
This project will yield new insights into the key drivers of hypertension and deliver a major breakthrough in knowledge about prevention and treatment among African and other population groups.
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Duración del proyecto: 67 meses
Fecha Inicio: 2018-01-31
Fecha Fin: 2023-08-31
Fecha Fin: 2023-08-31
Línea de financiación: concedida
El organismo H2020 notifico la concesión del proyecto el día 2023-08-31
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
ERC-2017-COG:
ERC Consolidator Grant
Cerrada
hace 7 años
Presupuesto
El presupuesto total del proyecto asciende a
2M€
Líder del proyecto
STICHTING AMSTERDAM UMC
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5
277.89K€ |
Participante