Hola,
Are you new here?

I have an account

Conecta con

+150K Projects

+300K Companies

+230 Financiaciones

¿Te ayudamos?

Ejemplos de búsqueda

Vídeos Explicativos

HyVIS

financed

Closed

Hybrid synapse for vision

"Degenerative diseases of the retina, such as Retinitis pigmentosa (RP) and age-related macular degeneration (AMD), hit light-sensitive photoreceptors and leave bipolar cells (BCs) deprived of light-dependent synaptic input. Neuro... see more

31/05/2025

IIT

3M€

Project Budget: 3M€

Project leader

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

Ver 6 Participantes

Financing granted El organismo H2020 notifico la concesión del proyecto The day 2025-05-31

FETOPEN-01-2018-2019-2020: FET-Open Challenging Current Thinki... Specific Challenge:to lay the foundations for radically new future technologies of any kind from vis...

I+D

Cerrada does 7 years

0% 100%

characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

6 Participantes

IIT

1.06M€ | Leader

400.93K€ | participant

TU/e

468.64K€ | participant

SORBONNE UNIVERSITE

400.63K€ | participant

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Project duration: 52 months Date Start: 2021-01-20
End date: 2025-05-31

Project leader

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 3M€

participation deadline Sin fecha límite de participación.

Project description "Degenerative diseases of the retina, such as Retinitis pigmentosa (RP) and age-related macular degeneration (AMD), hit light-sensitive photoreceptors and leave bipolar cells (BCs) deprived of light-dependent synaptic input. Neuronal degeneration starts affecting the presynaptic side of the synapse, while the denervated postsynaptic side preserves the ability to be activated. This project targets the recovery of the lost synaptic light-mediated input to BCs by artificially reproducing two of the key mechanisms involved in retinal image formation: glutamate release and high spatial resolution. BCs will be interfaced with plasmonic nanochannels filled with smart polymers able to release glutamate in response to optical stimuli, mimicking neurotransmitter release sites on presynaptic terminals. The functionalization of the nanochannels with appropriate adhesion molecules together with single cell genetic engineering will re-create the synaptic machinery and mediate contact formation between pre- and postsynaptic partners. No other attempts to recreate lost synapses by making an optically driven hybrid connection between a nano-sized neurotransmitter releasing device and the denervated postsynaptic cell have been attempted thus far. We propose stimulating neurons with a drastically novel method that surpasses the concept of electrical stimulation and that can go beyond single cell resolution to recreate lost synaptic connections with ""hybrid nanosynapses"". Moreover, the synergic combination of the proposed technologies paves the way for the breakthrough development of retinal prosthetics able to rescue the natural cell-specific connectivity of the inner retinal neurons."

Conecta tu I+D

Entra hoy

Forgot your password?

Financing

Companies

CTIs/Universidades

Projects

researchers

What is innovating.Works? Lose yourself in the best search engine for innovative companies you've ever seen, see how your competition is funded, connect with that partner you didn't know about, discover R&D projects that need you, and much, much more just a click away.

Smart Company-Financial Motor Innovating tiene un perfil tecnológico financiero de 400.000 empresas gracias al cual sabe a qué ayuda puede ir o no cualquier empresa de forma automática. Parece magia pero es tecnología.

Create your project and find partners ¿Tienes un proyecto y buscas un partner? Una Universidad, Centro Tecnológico, Consultoría? Este es tu sitio. Gracias al motor de búsqueda podemos recomendarte los mejores socios y ponerte en contacto con ellos.