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HLPA

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High-quality Laser-driven Proton beams for multidisciplinary Applications

Proton accelerators are in significant demand due to their widespread societal applications, for instance clinical cancer therapy, as the protons target deep-seated tumours with negligible damage to the surrounding healthy tissues... ver más

28/02/2025

FZU

166K€

Presupuesto del proyecto: 166K€

Líder del proyecto

FYZIKALNI USTAV AV CR V.V.I No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

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Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-07-20

HORIZON-MSCA-2021-PF-01-01: MSCA Postdoctoral Fellowships 2021 ExpectedOutcome:

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Cerrada hace 3 años

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No hay información privada compartida para este proyecto. Habla con el coordinador.

2 Participantes

FZU

166.28K€ | Lider

INFN

N.D. | Participante

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Duración del proyecto: 31 meses Fecha Inicio: 2022-07-20
Fecha Fin: 2025-02-28

Líder del proyecto

FYZIKALNI USTAV AV CR V.V.I No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 166K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Proton accelerators are in significant demand due to their widespread societal applications, for instance clinical cancer therapy, as the protons target deep-seated tumours with negligible damage to the surrounding healthy tissues. High capital and operational costs associated with the conventional accelerators make proton therapy poorly accessible, which has triggered interest in search for affordable alternatives. In this context, proton acceleration employing high power lasers has recently emerged as a promising alternative to the conventional techniques. In addition to their compactness and cost effectiveness, the laser-driven sources deliver high doses in an extremely short-time period (one billionth of the second), offering a unique prospect for radiobiological studies. The key challenge, however, is to overcome broad energy spread and large divergence of the laser-driven proton beams. This project aims to control these shortcomings by employing a novel target arrangement at PW class laser, which can effectively tailor the spatial and spectral profile of the beam at the source, importantly at high repetition rate (1 Hz). Transporting the beams to large distances away from the laser interaction region will be demonstrated by using a system of magnets, as a step towards building dedicated beamlines for multidisciplinary applications. The high-quality proton beams with energies required for therapeutic applications ( > 50MeV) will be deployed, for the first time, in in-vitro radiobiological studies on cancer breast cells at dose rate of ~ 100 Gy/min. The timeliness of the project is underpinned by the on-going developments of high-power laser facilities globally, e.g. the pillars of the pan-European Extreme Light Infrastructure, EPAC (UK), and ZEUS (USA). Notably, this cutting edge research would reinforce Europe's leading role in the development of 'all-optical' accelerators and and position me at the forefront of this emerging field.

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