Innovating Works

Resolve

Financiado
High performance affordable super resolution platform for the life sciences
Since their invention, super-resolution microscopy approaches are starting to transform research in the life sciences by enabling spatial resolution below the classical diffraction limit of light. In order to establish super-resol... Since their invention, super-resolution microscopy approaches are starting to transform research in the life sciences by enabling spatial resolution below the classical diffraction limit of light. In order to establish super-resolution microscopy as a standard research tool in the life sciences, researchers need to be able to readily access the three main technological pillars of super-resolution microscopy: instrumentation, software, and labeling probes. To date, the instrumentation is typically a very costly and complex microscope that requires skilled personnel for its operation. The software is either a non-user-friendly, but freely available solution, or a pricey commercial option that comes together with the costly microscope. Finally, the commercially available labeling probes so far suffer from several shortcomings in terms of performance and their multiplexing capability. During the ERC-funded project MolMap, we developed novel solutions for all three technological pillars. We constructed a prototype for an affordable super-resolution microscope with an estimated cost of only a fraction of the price of currently available commercial options. In addition, we developed a novel and user-friendly software platform as well as customizable labeling probes for sequential imaging of a multitude of targets. Together, these developments have the potential to be integrated into a high-performance and affordable super-resolution platform to become standard in life science laboratories such as nowadays cell culture microscopes. The aim of this Proof-of-Concept proposal is to further optimize the three technologies and to adapt the fully integrated platform to market needs. ver más
31/12/2019
149K€
Duración del proyecto: 18 meses Fecha Inicio: 2018-06-15
Fecha Fin: 2019-12-31

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2019-12-31
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-2017-PoC: ERC-Proof of Concept
Cerrada hace 7 años
Presupuesto El presupuesto total del proyecto asciende a 149K€
Líder del proyecto
LUDWIGMAXIMILIANSUNIVERSITAET MUENCHEN No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5