Innovating Works

HAND

Financiado
Heterogeneous Asymmetric Nanocluster-catalysis Design
Chirality plays a major role in several areas due to the different behavior of each enantiomeric form of a compound, critical in the pharmaceutical industry. Obtaining pure enantiomers is one of the most difficult challenges, in w... Chirality plays a major role in several areas due to the different behavior of each enantiomeric form of a compound, critical in the pharmaceutical industry. Obtaining pure enantiomers is one of the most difficult challenges, in which homogeneous asymmetric catalysis has achieved significant steps. Now it is time to undertake the challenge by heterogeneous enantioselective catalysis, implying great advantages in terms of sustainability, and offers further opportunities for in-depth understanding of mechanisms at the molecular level, relevant in multidisciplinary fields. However, successful design of such processes requires understanding and control of all relevant steps, which requires well-defined catalysts designed at atomic level. A new class of atomically precise nanomaterials that offers ample opportunities to explore chirality at the fundamental level, are the monolayer protected metal nanoclusters, which exhibit unexpected catalytic and intrinsically chiral properties. The HAND project aims to tackle actual challenges in heterogeneous asymmetric catalysis and achieve enantioselectivity with chiral nanoclusters on surfaces designed at atomic level. After creating chiral clusters active in homogeneous asymmetric reactions, we will control their immobilization on the support surface and their chiral properties. Such atomically precise chiral surfaces will allow us to overcome sensitivity barriers of available chiral spectroscopic techniques, improving studies of chirality at surfaces. Finally, having a well-defined chiral surface, asymmetric/enantioselective model reactions will be explored, aiming to obtain pure enantiomers. Each process step by itself represents a novel pioneering work in the field of nanoclusters and asymmetric catalysis, so far mostly unexplored. The fabrication and understanding of such a new class of chiral surfaces at the atomic level represent a breakthrough in knowledge relevant for materials science, nanotechnology and medicine. ver más
31/08/2029
TU WIEN
2M€
Perfil tecnológico estimado
Duración del proyecto: 64 meses Fecha Inicio: 2024-04-25
Fecha Fin: 2029-08-31

Línea de financiación: concedida

El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-04-25
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-2023-COG: ERC CONSOLIDATOR GRANTS
Cerrada hace 1 año
Presupuesto El presupuesto total del proyecto asciende a 2M€
Líder del proyecto
TECHNISCHE UNIVERSITAET WIEN No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5