Every year more than 60 million people live with Cardiovascular Disease (CVD), and more than 1.8 million people die as a result of CVD, accounting for 36% of all deaths. Among different types of CVD, heart attack and stroke are th...
ver más
30-11-2024:
Cataluña Gestión For...
Se ha cerrado la línea de ayuda pública: Gestión Forestal Sostenible para Inversiones Forestales Productivas para el organismo:
29-11-2024:
IDAE
En las últimas 48 horas el Organismo IDAE ha otorgado 4 concesiones
29-11-2024:
ECE
En las últimas 48 horas el Organismo ECE ha otorgado 2 concesiones
Descripción del proyecto
Every year more than 60 million people live with Cardiovascular Disease (CVD), and more than 1.8 million people die as a result of CVD, accounting for 36% of all deaths. Among different types of CVD, heart attack and stroke are the leading cause of death in the EU. The recognized guidelines identify the first one hour after the onset of a heart attack as the golden hour to receive proper medical assistance and prevent death or damage to organs. Hence, there is a vital need for a compact and easy-to-use biosensing platform that can be used outside hospital settings by the patient or the ambulance staff for diagnosis of heart attack within the golden hour. NT-pro-BNP is a desirable biomarker due to its fast release kinetics, higher circulation levels and lower fluctuations. Although significant advances in NT-pro-BNP biosensors generations have been achieved, these face some serious limitations as most of them cannot be used outside hospital settings, requiring physical attendance of patients which leads to losing time (beyond the golden hour) and increased risk of death. In this project, I propose – for the first time – a wearable and wireless system for early and quick diagnosis of a heart attack outside the hospital setting. The Heart Attack Monitoring Patch (HAMP) that I propose here, is composed of an AC Electrokinetic (ACEK)-based fast-response label-free NT-pro-BNP biosensor, microneedles array for interstitial fluid sampling and data processing, and wireless communication circuits. Although the ACEK phenomenon is a well-established method for the design of rapid biosensors, this is for the first time that the ACEK effect is employed by a wearable biosensing system for high speed (less than a minute) and low LOD (below 1 pg/mL) detection. The HAMP has a compact and conformal structure that is easy to use and can be used when patients feel the first symptoms of a heart attack and results can be conveniently sent to the nearby hospitals within the golden hour.
Seleccionando "Aceptar todas las cookies" acepta el uso de cookies para ayudarnos a brindarle una mejor experiencia de usuario y para analizar el uso del sitio web. Al hacer clic en "Ajustar tus preferencias" puede elegir qué cookies permitir. Solo las cookies esenciales son necesarias para el correcto funcionamiento de nuestro sitio web y no se pueden rechazar.
Cookie settings
Nuestro sitio web almacena cuatro tipos de cookies. En cualquier momento puede elegir qué cookies acepta y cuáles rechaza. Puede obtener más información sobre qué son las cookies y qué tipos de cookies almacenamos en nuestra Política de cookies.
Son necesarias por razones técnicas. Sin ellas, este sitio web podría no funcionar correctamente.
Son necesarias para una funcionalidad específica en el sitio web. Sin ellos, algunas características pueden estar deshabilitadas.
Nos permite analizar el uso del sitio web y mejorar la experiencia del visitante.
Nos permite personalizar su experiencia y enviarle contenido y ofertas relevantes, en este sitio web y en otros sitios web.