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Space and Motion

Financiado

Genetics and function of neuronal circuits controlling goal oriented movements

With this proposal I plan to dissect, at the genetic level, those circuits controlling goal-oriented movements in mice. In particular, we will focus on the very feature that makes goal-oriented movements so unique in the world of... ver más

30/06/2021

UKRI

1M€

Presupuesto del proyecto: 1M€

Líder del proyecto

UNITED KINGDOM RESEARCH AND INNOVATION No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 2 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2021-06-30

ERC-StG-2015: ERC Starting Grant

I+D

Cerrada hace 9 años

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2 Participantes

UKRI

1.50M€ | Lider

FABRICA ELECTROTECNICA JOSA

408.36K€ | Participante

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Duración del proyecto: 66 meses Fecha Inicio: 2015-12-14
Fecha Fin: 2021-06-30

Líder del proyecto

UNITED KINGDOM RESEARCH AND INNOVATION No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 1M€

Descripción del proyecto With this proposal I plan to dissect, at the genetic level, those circuits controlling goal-oriented movements in mice. In particular, we will focus on the very feature that makes goal-oriented movements so unique in the world of motor control, the spatial awareness of such movements, the fact that their execution is likely to obey a precise metric. I want to understand: (1) which neuronal circuits promote the initiation of targeted-movement and assess the genetic heterogeneity of these circuits. (2) Characterise the function of genetically identified circuit elements during movement execution, with the aim of understanding how the metric of motion is encoded. (3) Investigate how sensory maps and motor maps are aligned during development and probe their plasticity. In prospective (4), we aim to understand how changes in such circuits impinge on the development and evolution of innate behaviours such as predation. The French mathematician Henry Poincaré wrote that ‘The real space is motor space’. Embedded in this idea is the intimate relation between the perceptual encoding of space and motor execution. Accordingly, our research starts at the motor level and aims to move to the perceptual level.

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