Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

FunMagResBeacons

Financiado

Functionalized Magnetic Resonance Beacons for Enhanced Spectroscopy and Imaging

"This project will develop and demonstrate molecular agents called functional magnetic resonance beacons (fMRBs). These will provide a new set of versatile spectroscopic tools for the spatially resolved study of chemistry, biochem... ver más

30/09/2024

SOUTHAMPTON

3M€

Presupuesto del proyecto: 3M€

Líder del proyecto

UNIVERSITY OF SOUTHAMPTON No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 2 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2024-09-30

ERC-2017-ADG: ERC Advanced Grant

I+D

Cerrada hace 7 años

0% 100% 100%

2 Participantes

SOUTHAMPTON

2.76M€ | Lider

OS IRMANDIÑOS SOC. COOP GALE...

241.00K€ | Participante

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

CTQ2008-01110 IONES PARAMAGNETICOS EN RMN: SUPRESION SELECTIVA DE SEÑALES... 151K€ Cerrado

EQC2018-004665-P Actualización equipo de Resonancia Magnética Nuclear de 400... 206K€ Cerrado

HyperULFNMR Hyperpolarized ultra low field ULF magnetic resonance to d... 2M€ Cerrado

CSIC10-1E-413 Equipo de Resonancia Magnética Nuclear (400 MHz) para medida... 489K€ Cerrado

TRYP Transportable Hyperpolarization for Imaging 150K€ Cerrado

UNLV08-3E-015 Solicitud de financiación para la adquisición de un espectró... 525K€ Cerrado

Duración del proyecto: 76 meses Fecha Inicio: 2018-05-15
Fecha Fin: 2024-09-30

Líder del proyecto

UNIVERSITY OF SOUTHAMPTON No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 3M€

Descripción del proyecto "This project will develop and demonstrate molecular agents called functional magnetic resonance beacons (fMRBs). These will provide a new set of versatile spectroscopic tools for the spatially resolved study of chemistry, biochemistry, diffusion, flow and percolation inside opaque objects. The fMRB agents support hyperpolarized nuclear spin order, which generates enormously enhanced nuclear magnetic resonance (NMR) signals. The agents are designed to maintain such order for long times (between 5 minutes and several hours) in ambient temperature solution, enabling their transport deep inside opaque objects. The molecules are functionalized, so that they light up"" in an NMR or magnetic resonance imaging (MRI) experiment, upon triggering by specific chemical signals or physical conditions (sensory functionality), and may also to bind to selected molecular targets (binding functionality). One set of proposed realisations possesses lock-and-key functionality, meaning that the hyperpolarized nuclear spin order is locked into a form which is invisible in the NMR spectrometer, but which may be unlocked at any chosen time by applying a suitable radiofrequency pulse sequence. The following molecular moieties are proposed as storage modules: (1) molecular cages, such as functionalized C60 fullerenes, encapsulating noble gas atoms such as 3He; (2) spin clusters supporting long-lived states, such as pairs of 13C or 15N nuclei, in shielded molecular environments. The sensory moieties include tailored peptide sequences, which may be activated by the presence of particular proteases, while binding modules include moieties such as biotin. The agents are designed to be conveniently transportable in a hyperpolarized state. Potential long-term applications include in vivo molecular imaging by MRI. "

Conecta tu I+D

Entra hoy

¿Olvide mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores