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FUTURE-NHP

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Flexible and User defined Technologies for Unconstrained neural Recording Experi...

Flexible and User defined Technologies for Unconstrained neural Recording Experiments in Non Human Primates Some of the greatest today’s challenges in understanding human brain functions and dysfunctions are being tackled by using Non-Human Primates (NHPs), a unique and still unreplaceable model in neurophysiology because of their remar... ver más

31/08/2022

UNIVERSITA DEGLI S...

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

UNIVERSITA DEGLI STUDI DI PARMA No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

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Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2022-08-31

ERC-2020-POC: Call for proposals for ERC Proof of...

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3 Participantes

UNIVERSITA DEGLI STUDI DI PA...

92.50K€ | Lider

INERCO INGENIERIA TECNOLOGIA...

1.21M€ | Participante

ALU-FR

57.50K€ | Participante

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Duración del proyecto: 25 meses Fecha Inicio: 2020-07-28
Fecha Fin: 2022-08-31

Líder del proyecto

UNIVERSITA DEGLI STUDI DI PARMA No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 150K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Some of the greatest today’s challenges in understanding human brain functions and dysfunctions are being tackled by using Non-Human Primates (NHPs), a unique and still unreplaceable model in neurophysiology because of their remarkable anatomo-functional, cognitive and behavioural similarities to humans. Tethered neural recordings have been, so far, the virtually unique methodology available for these studies. Nonetheless, this approach 1) limits the range of behaviours and functions that can be investigated, 2) reduces the ecological validity of the results and 3) increases the public ethical concerns about the use of NHP, challenging the future of this still fundamental branch of science. This project (FUTURE-NHP) capitalizes on the preliminary findings of the ERCstg grant WIRELESS, in which we are developing a new approach to brain studies in freely-moving NHP with wireless technologies and video behavioural monitoring. The aim of FUTURE-NHP is the fabrication and pre-commercial testing of a new, 3D printed cranial device, allowing to easily and flexibly perform semi-chronic neural recordings from a fully customizable and interchangeable sets of multielectrode probes. With our partner SME we will perform, in parallel, a detailed evaluation of commercial opportunities for the developed device in a global (not just EU) perspective using clear IPR constructions and strategies. Furthermore, we will implement a software platform allowing end- users to design customized layouts of the device for custom-specific applications. The device will be optimized for (but not limited to) wireless recording experiments and will be made compatible with different types of probes and recording systems. By extending the range of affordable neuroscientific questions to unconstrained behaviors, FUTURE-NHP will improve the ecological validity of neurophysiological data and their translational value for humans, and contribute to make more ethically acceptable NHP fundamental research.

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