Hola,
¿eres nuevo aquí?

Registrate y conecta tu empresa con financiación pública, partners y proyectos.

FASTLabEx

Financiado

Fast Radio Labeling and Isotope Exchange

The impact of synthetic organic molecules on health, life quality and lifestyle is beyond doubt. It is therefore of fundamental importance to detect and quantify the fate of organic compounds and provide a precise risk/benefit ass... ver más

30/09/2025

CEA

2M€

Presupuesto del proyecto: 2M€

Líder del proyecto

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENER... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 2 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2020-04-24

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

ERC-2019-COG: ERC Consolidator Grant

I+D

Cerrada hace 5 años

0% 100% 100%

2 Participantes

CEA

2.00M€ | Lider

CORUGADOS AZPEITIA, S.L.U.

1.43M€ | Participante

Últimas noticias

30-11-2024: Cataluña Gestión For... Se ha cerrado la línea de ayuda pública: Gestión Forestal Sostenible para Inversiones Forestales Productivas para el organismo:

29-11-2024: IDAE En las últimas 48 horas el Organismo IDAE ha otorgado 4 concesiones

29-11-2024: ECE En las últimas 48 horas el Organismo ECE ha otorgado 2 concesiones

Duración del proyecto: 65 meses Fecha Inicio: 2020-04-24
Fecha Fin: 2025-09-30

Presupuesto del proyecto 2M€

Descripción del proyecto The impact of synthetic organic molecules on health, life quality and lifestyle is beyond doubt. It is therefore of fundamental importance to detect and quantify the fate of organic compounds and provide a precise risk/benefit assessment, before they reach the market and large public exposure. The traceless incorporation of carbon-14 allows tracking organic molecules and provides vital knowledge on their fate. This information is critical for pharmaceutical development, crop science and human food safety evaluation. Surprisingly, carbon radiolabeling still represents a bottleneck and an unsolved fundamental problem. In fact, current synthetic strategies are marred by several major drawbacks, including the generation of radioactive waste, being multi-step time-consuming and high resource-demanding. To circumvent such disadvantages, I present FASTLabEx, a novel approach for the straightforward preparation of carbon-labeled complex organic molecules that introduces the radioactive tag at the ultimate-stage of the synthesis. Inspired by efficient metal-catalyzed transformations, FASTLabEx makes use of a novel paradigm of carbon isotope exchange, defined as the selective replacement of molecular moieties into organic molecules, by reversible molecular deconstruction/reconstruction in presence of an appropriate radiolabeled moiety. FASTLabEx will explore this concept onto a large variety of functional groups and structural diversity, far beyond the case of carboxylic acids. This approach has the potential to streamline the radio-synthesis of pharmaceuticals and agrochemicals. Outcomes from FASTLabEx will have a tangible societal impact not only for the radiochemical community, but also for pharmaceutical and agrochemical industries and in fine the consumers and patients. In order to mitigate the risks inherent to the project, preliminary results demonstrate its feasibility.

Conecta tu I+D

Entra hoy

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores