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BehaEvoDevo

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Evolution of neuronal cell types development and circuitry in the insect visual...

Evolution of neuronal cell types development and circuitry in the insect visual system breaking down behavioural evolution into its constituent elements One of the holy grails of neuroscience is to understand how complex behaviours arise. However, surprisingly little is known about how behaviours evolve. My proposal will delve into Behavioural Evolution and Development (BehaEvoDev... ver más

31/08/2026

CNRS

2M€

Presupuesto del proyecto: 2M€

Líder del proyecto

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

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Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2020-10-30

ERC-2020-STG: ERC STARTING GRANTS

I+D

Cerrada hace 5 años

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No hay información privada compartida para este proyecto. Habla con el coordinador.

2 Participantes

CNRS

1.63M€ | Lider

STEEL BETON ESPAÑOLA

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Duración del proyecto: 70 meses Fecha Inicio: 2020-10-30
Fecha Fin: 2026-08-31

Líder del proyecto

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 2M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto One of the holy grails of neuroscience is to understand how complex behaviours arise. However, surprisingly little is known about how behaviours evolve. My proposal will delve into Behavioural Evolution and Development (BehaEvoDevo) in an unbiased and comprehensive way using the insect visual system as a model. The visual system of Drosophila has been described extensively in terms of cell type composition, development, circuitry, and behaviour. My expertise in this system will be the springboard to address four fundamental questions: 1) How different is the cell type composition in the brains of different animals? 2) How do the mechanisms that are responsible for neuronal development evolve and how do they affect neuronal diversity? 3) What are the differences in the circuitry that underlies specific behaviours in different animals? 4) How do differences in neuronal composition, neuronal features, or circuitry drive different behaviours? I will combine cutting edge techniques, such as single-cell sequencing, with advanced genetic tools in Drosophila, and adapt innovative tools for genetic manipulation and circuit function in different non-model insects. I will compare how cell type composition, neuronal specification and differentiation, as well as circuitry, affect specific behaviours. I will examine phylogenetically diverse insects to generate a deep understanding of the mechanisms that are most important for the evolution of different behaviours. Moreover, I will identify fundamental principles about how developmental processes, such as neuronal specification and differentiation, evolve to control different behaviours. The cumulative results of this proposal will offer the first comprehensive assessment of the mechanisms that drive evolution of new behaviours across insects; it will also generate a blueprint for the community to compare their data in different clades of the phylogenetic tree as well as to different sensory modalities.

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