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UNICELLSYS

Financiado

Cerrado

Eukaryotic unicellular organism biology systems biology of the control of cell...

Eukaryotic unicellular organism biology systems biology of the control of cell growth and proliferation The overall objective of UNICELLSYS is a quantitative understanding of fundamental characteristics of eukaryotic unicellular organism biology: how cell growth and proliferation are controlled and coordinated by extracellular and i... ver más

31/03/2013

UGOT - GOETEBORGS...

15M€

Presupuesto del proyecto: 15M€

Líder del proyecto

GOETEBORGS UNIVERSITET No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 18 Participantes

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2013-03-31 No tenemos la información de la convocatoria

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

18 Participantes

UGOT - GOETEBORGS UNIVERSITE...

0.00€ | Lider

UEDIN

N.D. | Participante

CHALMERS TEKNISKA HOGSKOLA A...

N.D. | Participante

FCC

N.D. | Participante

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Líder del proyecto

GOETEBORGS UNIVERSITET No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 15M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The overall objective of UNICELLSYS is a quantitative understanding of fundamental characteristics of eukaryotic unicellular organism biology: how cell growth and proliferation are controlled and coordinated by extracellular and intrinsic stimuli. Achieving an understanding of the principles with which bio-molecular systems function requires integrating quantitative experimentation with simulations of dynamic mathematical models. UNICELLSYS bring together a consortium of leading European experimental and computational systems biologists that will study cell growth and proliferation at the levels of cell population, single cell, cellular network, large-scale dynamic systems and functional module. Building computational reconstructions and dynamic models will involve different precise quantitative measurements as well as complementary approaches of mathematical modelling. A major challenge will be the generation of comprehensive dynamic models of the entire control system of cell growth and proliferation, which will require integration of smaller sub-models and reduction of complexity. Implementation of the models will allow observing responses to altered growth conditions zooming in seamlessly from populations consisting of cells of different replicative age and cell cycle stage via genome-wide molecular networks, large dynamic systems to detailed functional modules. Employing computational simulations combined with experimentation will allow discovering new and emerging principles of bio-molecular organisation and analysing the control mechanisms of cell growth and proliferation. The project will deliver new knowledge on fundamental eukaryotic biology as well as tools for quantitative experimentation and modelling. Detailed plans for dissemination and exploitation will ensure that UNICELLSYS will have major impact on the development of Systems Biology in Europe ensuring a competitive advantage of Europe in dynamic quantitative modelling of bio-molecular processes.

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