Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

SENSORY INNERVATION

Financiado

Cerrado

Establishment and refinement of sensory innervation in the lateral line system o...

Establishment and refinement of sensory innervation in the lateral line system of the zebrafish The establishment of sensory-organ innervation is crucial for behaviour, social interactions and survival. Neuronal arborisation is dictated by signals that guide neurites to their appropriate targets in combination with the spati... ver más

30/04/2011

FUNDACIO PRIVADA C...

153K€

Presupuesto del proyecto: 153K€

Líder del proyecto

FUNDACIO PRIVADA CENTRE DE REGULACIO GENOMICA Otras actividades deportivas asociacion

TRL 4-5 | 50K€

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2011-04-30 No tenemos la información de la convocatoria

0% 100% 100%

Características del participante

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

FUNDACIO PRIVADA CENTRE DE R...

0.00€ | Lider

Proyectos interesantes

SENSORINEURAL

Medical Technol...

Applied Physics

1M€ Cerrado

PGC2018-095663-B-I00

Medical Technol...

Applied Physics

191K€ Cerrado

OPTOLOCO

Medical Technol...

Applied Physics

1M€ Cerrado

PID2021-124415NB-I00

Medical Technol...

Applied Physics

127K€ Cerrado

ZEBRAFISHFOREBRAIN

Medical Technol...

Applied Physics

242K€ Cerrado

FJC2021-046529-I

Medical Technol...

Applied Physics

65K€ Cerrado

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Líder del proyecto

FUNDACIO PRIVADA CENTRE DE REGULACIO GENOMICA Otras actividades deportivas asociacion

TRL 4-5 | 50K€

Presupuesto del proyecto 153K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The establishment of sensory-organ innervation is crucial for behaviour, social interactions and survival. Neuronal arborisation is dictated by signals that guide neurites to their appropriate targets in combination with the spatial distribution of the target cells. To date, most emphasis has been placed on the genetic bases of neuronal-type specification and organ formation during embryonic development and, consequently, there is a serious gap in our knowledge about the long-term dynamics of organ innervation. To advance towards this goal, we will need to elucidate whether and how neuronal activity and sensory organ architecture can modulate neural arborisation. Vertebrate sensory organs represent an excellent model to study the establishment and maintenance of organ innervation. To investigate these processes, I have chosen the zebrafish mechanosensory lateral line as a model system. In general, planar polarized sensory hair cells in each unit of the lateral line, called neuromast, receive innervation by two afferent neurons. Hair cells can regenerate and re-innervate very rapidly, providing a simple model of sensory neurons arborisation whose dynamics can be visualized in vivo over long periods and under normal or altered physiological conditions. To investigate the mechanisms that govern the acquisition and maintenance of hair-cell innervation, I will conduct a systematic and comprehensive study of the processes that underlie the elaboration and remodelling of sensory-neuronal architecture in the lateral-line organ. I will perform high-resolution live imaging combined with sophisticated techniques to permit spatio-temporal control of protein expression. The findings derived from these studies shall reveal the mechanisms by which animals maintain sensory abilities throughout their entire lives.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores