ENTANGLED-TM-ALKANE
Financiado
Entangled pincer ligand architectures and their application in the transition me...
Entangled pincer ligand architectures and their application in the transition metal mediated activation of alkanes
The selective transformation of alkanes is an area of contemporary importance with wide-ranging implications for organic synthesis and the effective use of petroleum resources. While homogeneous transition metal catalysis is a pot...
The selective transformation of alkanes is an area of contemporary importance with wide-ranging implications for organic synthesis and the effective use of petroleum resources. While homogeneous transition metal catalysis is a potentially powerful means for achieving this objective, the fundamental organometallic chemistry of alkane activation reactions has proven to be exceedingly difficult to investigate due to the weakly interacting nature of alkanes. To address this knowledge gap and provide the foundation for future advancement of the field, ENTANGLED-TM-ALKANE outlines a systematic approach for the study of pivotal sigma–alkane complex intermediates; nominally transient and extremely reactive metal-alkane adducts formed through coordination of an intact C–H bond to the metal centre. Inspired from supramolecular chemistry, the approach involves the innovative use of systems containing alkane substrates held in close proximity to reactive metal centres through mechanical entanglement within supporting tridentate macrocyclic ‘pincer’ ligands (i.e. alkane based [2]rotaxanes and [2]catenanes). Through the interwoven topology of these systems, problematic dissociation reactions of sigma–alkane complexes will be circumvented, facilitating isolation and ultimately enabling their structure and reaction chemistry to be probed in much greater detail than has been previously possible. The project objectives are to: (a) develop and use new synthetic (supramolecular) methodologies for the preparation of these mechanically interlocked metal-alkane assemblies; (b) systematically investigate the organometallic chemistry of the metal centre and its interaction with the entangled alkane; and through variation of the macromolecules’ components (macrocycle donors and geometry, alkane, metal), (c) compile a definitive and unprecedented body of qualitative and quantitative structure-activity relationships for the activation alkanes using transition metals.
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Duración del proyecto: 67 meses
Fecha Inicio: 2015-02-17
Fecha Fin: 2020-09-30
Fecha Fin: 2020-09-30
Línea de financiación: concedida
El organismo H2020 notifico la concesión del proyecto el día 2020-09-30
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
ERC-StG-2014:
ERC Starting Grant
Cerrada
hace 10 años
Presupuesto
El presupuesto total del proyecto asciende a
2M€
Líder del proyecto
UNIVERSITY OF WARWICK
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5
10.27M€ |
Participante