Hola,
¿eres nuevo aquí?

Registrate y conecta tu empresa con financiación pública, partners y proyectos.

TB-EPF

Financiado

Enhanced Place Finding EPF of TB transmission hotspots

TB is transmitted via person-to-person aerosols. Recent studies suggests that in TB endemic areas up to 70% of transmission events take place outside the household in public places. Moreover, TB transmission is unequally spatially... ver más

28/02/2019

ITM

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

INSTITUUT VOOR TROPISCHE GENEESKUNDE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 6 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2019-02-28

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

ERC-PoC-2016: ERC-Proof of Concept-2016

I+D

Cerrada hace 8 años

0% 100% 100%

6 Participantes

ITM

69.52K€ | Lider

SOCIEDAD DE VALIDACIoN DE SI...

103.80K€ | Participante

LSHTM

31.66K€ | Participante

Proyectos interesantes

PID2019-104437GB-I00 MODELIZACION MATEMATICA DE DINAMICAS DE EPIDEMIAS Y POBLACIO... 28K€ Cerrado

LEAPS Integrating Multi-Disciplinary Expertise in a Learning and A... 3M€ Cerrado

MOBVEC Mobile Bio-Lab to support first response in Arbovirus outbre... 3M€ Cerrado

FIND-TB Development and Validation of ‘findtb’, A Novel Digital Tool... 2M€ Cerrado

EpiGen Ethiopia BUILDING SCALABLE PATHOGEN GENOMIC EPIDEMIOLOGY FOR ETHIOPIA 5M€ Cerrado

RYC2021-031613-I Disease Ecology and Epidemiological Modelling of pathogen tr... 236K€ Cerrado

Últimas noticias

30-11-2024: Cataluña Gestión For... Se ha cerrado la línea de ayuda pública: Gestión Forestal Sostenible para Inversiones Forestales Productivas para el organismo:

29-11-2024: IDAE En las últimas 48 horas el Organismo IDAE ha otorgado 4 concesiones

29-11-2024: ECE En las últimas 48 horas el Organismo ECE ha otorgado 2 concesiones

Duración del proyecto: 18 meses Fecha Inicio: 2017-08-25
Fecha Fin: 2019-02-28

Líder del proyecto

INSTITUUT VOOR TROPISCHE GENEESKUNDE

TRL 4-5

Presupuesto del proyecto 150K€

Descripción del proyecto TB is transmitted via person-to-person aerosols. Recent studies suggests that in TB endemic areas up to 70% of transmission events take place outside the household in public places. Moreover, TB transmission is unequally spatially distributed and occurs in transmission hotspot areas. Mathematical models consequently demonstrated that identifying hotspots and blocking within-hotspot-transmission through targeted public health interventions will be the most efficient way of lowering the TB burden. In the present PoC proposal we aim to complement the population-based Enhanced-Case-Finding intervention tested in the INTERRUPTB study, with a spatially more targeted Enhanced-Place-Finding (EPF) approach to identify transmission hotspots in an unbiased fashion. Using traditional methods to find transmission hotspots can only be done retrospectively after years of data collection. Therefore we propose a novel EPF strategy to detect transmission hotspots in real-time using phone-tracking technology to establish a spatial map of aggregated TB patients movements. Within the ERC-funded INTERRUPTB study in The Gambia, we sequenced 2000 mycobacterial isolates, which allows us to establish a bacterial genetic transmission network. Within the PoC proposal, we seek to reconsent these patients to analyze their everyday movements using classical contact investigation complemented by phone tracking, to determine which public places have an increased risk of TB transmission. We aim to demonstrate that phone tracking of TB patients can be a cheap, easy, and, most importantly, prospective TB transmission hotspots identification tool, no longer requiring molecular epidemiological investigations. Such a finding can ultimately be developed into an app that warns national TB programs of early TB outbreaks, so that early public health measures like increased ventilation and active case finding can be initiated. This approach can furthermore be applied to other infectious diseases.

Conecta tu I+D

Entra hoy

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores