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Engineering Extracellular Matrices for Controlling Structure and Dynamics of Lip...
Engineering Extracellular Matrices for Controlling Structure and Dynamics of Lipid Bilayer Membranes
Cell membrane is the most critical element that is common to all biological systems. This five-nanometer-thick highly flexible lipid bilayer is known to govern numerous vital cellular processes including endocytosis, exocytosis, e...
Cell membrane is the most critical element that is common to all biological systems. This five-nanometer-thick highly flexible lipid bilayer is known to govern numerous vital cellular processes including endocytosis, exocytosis, enzyme activity, ion transport, cell-cell communication and cell division. Understanding and controlling multiscale structure and dynamics of the cell membrane is, hence, the key to regulate these crucial activities. So far, proposed approaches to tuning membrane dynamics, leading to its fluidity and stiffness, are based exclusively on modification of the bilayer composition that is highly cell specific. In this project, the researcher will use his previous research experience in harmony with expertise of the supervisor to uncover a novel and mechanistic way for regulating the dynamics of the lipid bilayers via engineering complex extracellular microenvironment. Beside its highly interdisciplinary and fundamental nature, this research has a significant potential to open up a new practical pathway to cure membrane-associated diseases, including but not limited to type-2 diabetes, cancer and Alzheimer. This research action will be a great opportunity for the researcher to acquire new scientific expertise, grow his worldwide collaboration network, practice key project management skills and effectively disseminate research outcomes - all of which are essential for being a successful independent academic.
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Duración del proyecto: 26 meses
Fecha Inicio: 2020-03-27
Fecha Fin: 2022-05-31
Fecha Fin: 2022-05-31
Línea de financiación: concedida
El organismo H2020 notifico la concesión del proyecto el día 2022-05-31
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
WF-02-2019:
Widening Fellowships
Cerrada
hace 5 años
Presupuesto
El presupuesto total del proyecto asciende a
145K€
Líder del proyecto
KOC UNIVERSITY
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5
931.10K€ |
Participante