Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

TheranoXome

Financiado

Engineered Exosomes for Stimuli-responsive Image-guided Drug delivery for Cancer...

Engineered Exosomes for Stimuli-responsive Image-guided Drug delivery for Cancer Theranostic applications. The primary objective of this project is to engineer a non-immunogenic cell-membrane mimicking drug delivery vehicle for remote-controlled precision drug delivery. This will be achieved by encapsulating stimuli-responsive & contra... ver más

31/08/2025

USC

181K€

Presupuesto del proyecto: 181K€

Líder del proyecto

UNIVERSIDAD DE SANTIAGO DE COMPOSTELA No se ha especificado una descripción o un objeto social para esta compañía.

Total investigadores 235

Ver 2 Participantes

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-08-04

HORIZON-MSCA-2021-PF-01-01: MSCA Postdoctoral Fellowships 2021 ExpectedOutcome:

I+D

Cerrada hace 3 años

0% 100%

2 Participantes

USC

181.15K€ | Lider

FUNDACION INSTITUTO DE INVES...

N.D. | Participante

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

PCI2021-122091-2B ENGINEERED EXOSOMES FOR STIMULI-RESPONSIVE IMAGE-GUIDED DRUG... 161K€ Cerrado

PID2020-112685RB-I00 NANOMEDICINAS BASADAS EN NANOPARTICULAS PARA INMUNOTERAPIA E... 249K€ Cerrado

PID2020-118448RB-C22 DESARROLLO DE NANOSISTEMAS MULTIFUNCIONALES BASADOS EN METAL... 121K€ Cerrado

MAT2011-26851-C02-01 INDUCCION DE MUERTE DE CELULAS TUMORALES MEDIANTE ACTIVACION... 90K€ Cerrado

CTQ2017-88446-R NANOTRANSPORTADORES PARA LA ADMINISTRACION DE FARMACOS MEDIA... 94K€ Cerrado

DIASHUTTLE Raman Active, Smart Diatom Frustules as Next Generation Mult... 236K€ Cerrado

Duración del proyecto: 36 meses Fecha Inicio: 2022-08-04
Fecha Fin: 2025-08-31

Líder del proyecto

UNIVERSIDAD DE SANTIAGO DE COMPOSTELA No se ha especificado una descripción o un objeto social para esta compañía.

Total investigadores 235

Presupuesto del proyecto 181K€

Descripción del proyecto The primary objective of this project is to engineer a non-immunogenic cell-membrane mimicking drug delivery vehicle for remote-controlled precision drug delivery. This will be achieved by encapsulating stimuli-responsive & contrast enhancing nanoparticles and drug cargo into endogenous exosomes to develop a therapeutic-cum-diagnostic exosomal system viz; TheranoXome for image-guided stimuli-responsive drug delivery. Such bio-mimetic TheranoXomes if realized will have wide applicability as a universal drug-delivery agent. The project entails three steps: (1) Synthesizing TheranoXomes by template assisted loading of chemotherapeutic drugs, light responsive thermoplasmonic gold nanorods and magnetic nanoparticles as magnetic resonance imaging agents into exosomes; (2) (Bio-)Physicochemical characterization of TheranoXomes including colloidal properties, biomimetics, immuno-compatibility, light-triggered drug release, magnetism (imaging and magnetic guided enrichment) and in vitro studies (2D and 3D cell cultures); (3) Application of TheranoXomes in vivo in a breast tumor bearing mice model. I (the ER) will prepare, characterize and test the materials and application proposed, with the support of a multidisciplinary hub of specialists. The prime training aim of TheranoXome is to provide me with a solid foundation in biomaterials, which will support my future career endeavours, both in the academia or industry, to be an independent researcher, a founder of a start-up company or to become key player in the biomaterials sector. I will be hosted by the Centre for Research in Biological Chemistry and Molecular Materials (CiQUS) of the University of Santiago de Compostela, a cutting-edge multidisciplinary research centre at the interface of chemistry, biomedicine and molecular materials. The training will be further strengthened by one secondment (6 months) focused on in vivo (drug delivery and imaging) studies (Health Research Institute of Santiago de Compostela - IDIS).

Conecta tu I+D

Entra hoy

¿Olvide mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores