ETOXPT
Financiado
Emergent toxins on the Portuguese coast occurrence transfer kinetics and toxic...
The occurrence of toxins typical from tropical environments in European Union (EU) temperate coastal waters has been sporadically reported in the past years, usually preceded by human intoxication episodes. Therefore, in order to...
The occurrence of toxins typical from tropical environments in European Union (EU) temperate coastal waters has been sporadically reported in the past years, usually preceded by human intoxication episodes. Therefore, in order to avoid public health impacts, there is a need for adequate monitoring programs, establishing appropriate legislation, and for optimizing effective methods for the analysis of these toxins. However, due to the very limited quantitative data and the lack of validated analytical methodology, risk associated with the exposure to emergent toxins in EU is currently not possible to determine. In ETOXPT, we will assess the current situation on the incidence and routes of exposure of emergent toxins (i.e. ciguatoxins, CTXs; tetrodotoxin, TTX; palytoxins, PLTXs; and ß-methylamino-L-alanine, BMAA) in Portuguese coastal waters using reliable LC-MS/MS methods. Additionally, the relationship of emergent toxins concentrations and profiles within trophic levels will be evaluated. These field data will be complemented with a mesocosm experiment, in which the potential of CTXs transfer, biotransformation and biodegradation along the food web will be predicted. We will also evaluate the cytotoxicity of individual PLTXs and CTXs analogues. Concurrently, we will develop innovative approaches to analyze the emergent toxins using nanocontainers. ETOXPT will be useful to advance understanding of emergent toxins kinetics, both within individuals and among trophic levels and could support the development of predictive models of risk assessment and contribute to the integration of emergent toxins in shellfish monitoring programs.
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Duración del proyecto: 50 meses
Fecha Inicio: 2020-03-31
Fecha Fin: 2024-05-31
Fecha Fin: 2024-05-31
Línea de financiación: concedida
El organismo H2020 notifico la concesión del proyecto el día 2024-05-31
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
WF-02-2019:
Widening Fellowships
Cerrada
hace 5 años
Presupuesto
El presupuesto total del proyecto asciende a
148K€
Líder del proyecto
CENTRO DE CIENCIAS DO MAR DO ALGARVE
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5
1.42M€ |
Participante