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Elucidating the causes and consequences of the global pattern of epigenetic vari...
Elucidating the causes and consequences of the global pattern of epigenetic variation in Arabidopsis thaliana Epigenetics continues to fascinate, especially the notion that it blurs the line between nature and nurture and could make Lamarckian adaptation via the inheritance of acquired characteristics possible. That this is in principle p... Epigenetics continues to fascinate, especially the notion that it blurs the line between nature and nurture and could make Lamarckian adaptation via the inheritance of acquired characteristics possible. That this is in principle possible is clear: in the model plant Arabidopsis thaliana (Thale cress), experimentally induced DNA methylation variation can be inherited and affect important traits. The question is whether this is important in nature. Recent studies of A. thaliana have revealed a pattern of correlation between levels of methylation and climate variables that strongly suggests that methylation is important in adaptation. However, somewhat paradoxically, the experiments also showed that much of the variation for this epigenetic trait appears to have a genetic rather than an epigenetic basis. This suggest that epigenetics may indeed be important for adaptation, but as part of a genetic mechanism that is currently not understood. The goal of this project is to determine whether the global pattern of methylation has a genetic or an epigenetic basis, and to use this information to elucidate the ultimate basis for the global pattern of variation: natural selection. ver más
31/05/2024
GMI
2M€
Duración del proyecto: 72 meses Fecha Inicio: 2018-05-15
Fecha Fin: 2024-05-31

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2024-05-31
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-2017-ADG: ERC Advanced Grant
Cerrada hace 7 años
Presupuesto El presupuesto total del proyecto asciende a 2M€
Líder del proyecto
GREGOR MENDEL INSTITUT FUR MOLEKULARE PFLANZE... No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5