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iCON

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Elucidating inner cells contribution to pavement cell shape acquisition in Arabi...

Elucidating inner cells contribution to pavement cell shape acquisition in Arabidopsis In plants, the outermost epidermal cell layer is critical for protecting the entire plant against external threats such as rain, wind and pathogens. The plant epidermis is a complex tissue consisting of multiple cell types, all wi... ver más

22/06/2027

SWEDISH UNIVERSITY...

223K€

Presupuesto del proyecto: 223K€

Líder del proyecto

SVERIGES LANTBRUKSUNIVERSITET No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-04-10

HORIZON-MSCA-2023-PF-01-01: MSCA Postdoctoral Fellowships 2023 Expected Outcome:Project results are expected to contribute to the following outcomes:

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1 Participantes

SWEDISH UNIVERSITY OF AGRICU...

222.73K€ | Lider

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Duración del proyecto: 38 meses Fecha Inicio: 2024-04-10
Fecha Fin: 2027-06-22

Líder del proyecto

SVERIGES LANTBRUKSUNIVERSITET No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 223K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto In plants, the outermost epidermal cell layer is critical for protecting the entire plant against external threats such as rain, wind and pathogens. The plant epidermis is a complex tissue consisting of multiple cell types, all with different shapes, functions and developmental trajectories. Although studied in isolation, our understanding of how these cells interact to ensure tissue integrity is poor, but at present, the outermost jigsaw-puzzle-shaped pavement cells have emerged as key players. Recent findings in the host lab suggest that the diverse physical and/or mechanochemical nature of the cell wall is crucial for pavement cell-shape acquisition, and thus under influence of the underlying tissue layers. However, yet the identity of the putative signals derived from inner cell layers, defining the shape of epidermal cells and the integrity of the multilayered leaf tissue, remains to be explored. Hence, in iCON I will join the Robert (host) lab to disentangle the signaling networks and mechanical constraints of inner mesophyll cells that determine epidermal pavement cell shape and organogenesis of the leaf, using a suite of novel and multidisciplinary approaches in the model plant Arabidopsis thaliana. Specifically, I will acquire new skills in cutting-edge microscopy, cell biology and biomechanics to generate a high-resolution 3D map and uncover mechanical/physical cues, and leverage my expertise in transcriptomics, genetics and molecular biology to determine molecular components, together allowing me to decipher the overall mechanism via which mesophyll cells orchestrate pavement cell shape acquisition. Besides contributing new knowledge, iCON will allow me to expand my scientific expertise and gain key transferrable skills, boosting my strive to become a research leader. Ultimately, knowledge on how plants maintain tissue integrity can support the development of stress-resilient plants and thus contribute to a sustainable agriculture in a changing climate.

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