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Electrochemically Driven Organocatalytic Transformations of Alcohols Thiols and...

Electrochemically Driven Organocatalytic Transformations of Alcohols Thiols and Disulfides The purpose of this research, set in the context of synthetic organic chemistry, is to develop unprecedented methods for electrochemically driven cleavage and subsequent functionalization of C–O and C–S bonds in alcohols, thiols a... see more

30/11/2029

KTH

2M€

Project Budget: 2M€

Project leader

KUNGLIGA TEKNISKA HOEGSKOLAN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

Financing granted El organismo HORIZON EUROPE notifico la concesión del proyecto The day 2024-10-01

ERC-2024-STG: ERC STARTING GRANTS Scope:Objectives

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Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

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1 Participantes

KTH

1.50M€ | Leader

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Project duration: 61 months Date Start: 2024-10-01
End date: 2029-11-30

Project leader

KUNGLIGA TEKNISKA HOEGSKOLAN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 2M€

participation deadline Sin fecha límite de participación.

Project description The purpose of this research, set in the context of synthetic organic chemistry, is to develop unprecedented methods for electrochemically driven cleavage and subsequent functionalization of C–O and C–S bonds in alcohols, thiols and disulfides using organocatalysts based on phosphorus and sulfur. These radical methods will serve as keys to unlock the potential of the targeted compound classes as feedstocks for synthesis of functional organic compounds, e.g., pharmaceuticals, as well as for biomass valorization processes. Due to the complexity of the targeted transformations, the scarcity of available methods and the novelty of the outlined approach, the research will expand the synthetic toolbox, enable new retrosynthetic disconnections and late-stage (de)functionalization of, e.g., carbohydrates and peptides. Combined with the integrated mechanistic studies, the research will have a significant impact from a fundamental science perspective, as well as enable new synthetic applications. The project is divided into two main topics, each sized for one PhD student and one postdoc working together on the outlined work packages. The proposed research is supported by preliminary results that indicate its viability.

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