Hola,
Are you new here?

ElectroBor

financed

Electrochemical Borylation via Borylene Species: Bridging a Gap in Synthetic Che...

Electrochemical Borylation via Borylene Species: Bridging a Gap in Synthetic Chemistry Carbenoids (carbene and nitrene) have revolutionized the field of organic chemistry, reshaping and improving the molecular construction landscape and unveiling previously inaccessible reaction pathways. This chemistry has massivel... see more

30/09/2029

WEIZMANN

1M€

Project Budget: 1M€

Project leader

WEIZMANN INSTITUTE OF SCIENCE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

Financing granted El organismo HORIZON EUROPE notifico la concesión del proyecto The day 2024-10-01

ERC-2024-STG: ERC STARTING GRANTS Scope:Objectives

I+D

Cerrada does 1 year

0% 100%

characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

Participantes

WEIZMANN

Leader

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Project duration: 59 months Date Start: 2024-10-01
End date: 2029-09-30

Project leader

WEIZMANN INSTITUTE OF SCIENCE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 1M€

participation deadline Sin fecha límite de participación.

Project description Carbenoids (carbene and nitrene) have revolutionized the field of organic chemistry, reshaping and improving the molecular construction landscape and unveiling previously inaccessible reaction pathways. This chemistry has massively simplified the synthesis of complex molecular structures, such as pharmaceuticals, agrochemicals, and polymers. In contrast with the essential role of carbenes and nitrenes, the boron analogue - borylene - has received limited attention in synthetic chemistry. A basic understanding of borylene reactivity has hindered its utilization in organic synthesis, primarily because of its synthetically challenging formation.This proposal aims to harness electrochemistry as a novel synthetic approach for the controlled generation of borylenes. This chemoselective platform will determine the critical factors that influence the reactivity of borylene intermediates and will enable the use of new borylation techniques previously out of reach of chemists. Having successfully demonstrated the first example of electrochemical borylene formation, we anticipate the emergence of various novel borylation techniques, among others, (i) the synthesis of underexplored strained three-membered boracycles by cycloaddition reactivity, unlocking access to novel classes of molecules, and (ii) the activation of ubiquitous bonds through boron insertion into C-C, which will utilize unprecedented retrosynthetic logic for ring expansion and 1,n-substituted chemical motifs, thus shortening the synthetic scheme of functional materials.Drawing inspiration from the remarkable impact of carbenoids across a multitude of chemistry domains, we envision that the electrosynthesis of borylenes will empower chemists to employ these reactive species to unlock access to entirely underexplored classes of molecules and will provide profound insights into borylene reactivity, consequently charting a captivating course towards undiscovered realms in chemical synthesis.

Conecta tu I+D

Entra hoy

Forgot your password?

Financing

Companies

CTIs/Universidades

Projects

researchers