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ALLEGRO

Financiado

Cerrado

Early and late health risks to normal healthy tissues from the use of existing a...

Early and late health risks to normal healthy tissues from the use of existing and emerging techniques for radiation therapy Curative cancer treatment with radiation seeks to optimise the magnitude of the radiation dose to the treatment volume while restricting the dose to normal healthy tissue. With an increasing population of surviving cancer patient... ver más

31/03/2011

UNIPV

4M€

Presupuesto del proyecto: 4M€

Líder del proyecto

UNIVERSITA DEGLI STUDI DI PAVIA No se ha especificado una descripción o un objeto social para esta compañía.

Fecha límite participación Sin fecha límite de participación.

Ver 12 Participantes

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2011-03-31 No tenemos la información de la convocatoria

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

12 Participantes

UNIPV

0.00€ | Lider

CHALMERS TEKNISKA HOGSKOLA A...

N.D. | Participante

KU Leuven

N.D. | Participante

TUD

N.D. | Participante

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Líder del proyecto

UNIVERSITA DEGLI STUDI DI PAVIA No se ha especificado una descripción o un objeto social para esta compañía.

Presupuesto del proyecto 4M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Curative cancer treatment with radiation seeks to optimise the magnitude of the radiation dose to the treatment volume while restricting the dose to normal healthy tissue. With an increasing population of surviving cancer patients treated with radiation therapy, the harmful effects of the radiation to normal tissue are becoming more evident. The ALLEGRO project will address the many aspects of normal healthy tissue damage that are not yet well understood in both conventional treatment techniques and emerging techniques (protons, heavy ions). The project will include measurement of radiation doses outside the treatment volume and investigation of the accuracy of methods of dose calculation in this region. The extensive existing databases of radiation treatments and outcomes will be used to investigate models of normal tissue damage and second primary cancer. The measurements and data analysis will be supported by theoretical modelling and surveys to develop the link between radiobiological mechanisms and empirical normal tissue complication (NTCP) models, and to extend conventional models to apply to the emerging techniques. The project is restricted to two years, so there will be a limit to the amount of new research possible. Therefore an essential part of the project will be to engage a forum of experts to redefine the current knowledge on normal tissue damage following radiotherapy, identify gaps in the knowledge and make recommendations for future research, data collection, and technological developments. The final report will consist of a series of focused documents directed to clinicians (for the application of normal tissue risks in treatment optimisation), equipment manufacturers (recommendations on safety design), and the research community (summary of knowledge and recommendations on data collection and project proposals).

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