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DyNAmics

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Dynamic synthetic molecular duplexes

Precise control of macroscopic properties at molecular level is one of the biggest challenges of modern science. Nature accomplishes this by adding information to matter, and organizes chemical system of nonliving components into... see more

28/02/2019

THE CHANCELLOR MAS...

183K€

Project Budget: 183K€

Project leader

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UN... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo H2020 notifico la concesión del proyecto The day 2019-02-28

MSCA-IF-2016: Individual Fellowships Objective:The goal of the Individual Fellowships is to enhance the creative and innovative potential...

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Cerrada does 9 years

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

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2 Participantes

THE CHANCELLOR MASTERS AND S...

183.45K€ | Leader

2B BLACKBIO

215.99K€ | participant

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Project duration: 24 months Date Start: 2017-02-22
End date: 2019-02-28

Project leader

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UN... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 183K€

participation deadline Sin fecha límite de participación.

Project description Precise control of macroscopic properties at molecular level is one of the biggest challenges of modern science. Nature accomplishes this by adding information to matter, and organizes chemical system of nonliving components into living, biological systems. Achieving a deep knowledge on the appropriate manipulation of the intermolecular non-covalent interactions, will allow chemistry to be not only the science of the structure and transformation of matter, but also an information science, involving the storage of information at the molecular level. Inspired by the most fascinating nature’s information system, the DNA, DyNAmics will perform a modular and highly flexible synthesis of novel information carrying monomers, able to self-organize in duplex structure, through both covalent and non-covalent bonds formation. The reliability, robustness and the dynamic formation of H-bond based duplex, together with the template ability in a dynamic combinatorial system, will be deeply investigated. By quantitative assessment of multivalent recognition of complementary sequences and imperfections in the duplex formation of non-complementary and defective sequences, valuable information on the structural features and fidelity of supramolecular assembly formation of various sequences will be obtained. Reliable formation of dynamic synthetic duplexes would allow precise control over supramolecular interactions and will lay the foundation for formation of smart advanced materials with unprecedented properties, such as innovative data storage materials and new Constitutional Dynamic Materials. Furthermore this will be crucial for the development of efficient template directed synthesis for information encoding molecules, and it will provide information to answer to important questions regarding the formation of duplex encoding information, in a enzyme free system, such as the prebiotic word.

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