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DVD-readable opto-electrochemical Lab-on-a-Disc as small-factor wearable wireles...

DVD-readable opto-electrochemical Lab-on-a-Disc as small-factor wearable wireless medical device for obesity management Obesity is one of the most common and costly chronic disorder worldwide, and is a causal or a strong risk factor for several comorbidities, as type 2 diabetes (T2D), which is now reaching epidemic proportions. To monitor multifact... ver más

31/07/2026

STOCKHOLMS UNIVERS...

278K€

Presupuesto del proyecto: 278K€

Líder del proyecto

STOCKHOLMS UNIVERSITET No se ha especificado una descripción o un objeto social para esta compañía.

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Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-03-22

HORIZON-MSCA-2022-PF-01-01: MSCA Postdoctoral Fellowships 2022 ExpectedOutcome:

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Cerrada hace 2 años

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5 Participantes

STOCKHOLMS UNIVERSITET

278.41K€ | Lider

KTH

N.D. | Participante

BioBee_Tech

N.D. | Participante

CSIC

N.D. | Participante

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Duración del proyecto: 40 meses Fecha Inicio: 2023-03-22
Fecha Fin: 2026-07-31

Líder del proyecto

STOCKHOLMS UNIVERSITET No se ha especificado una descripción o un objeto social para esta compañía.

Presupuesto del proyecto 278K€

Descripción del proyecto Obesity is one of the most common and costly chronic disorder worldwide, and is a causal or a strong risk factor for several comorbidities, as type 2 diabetes (T2D), which is now reaching epidemic proportions. To monitor multifactorial disorders such as obesity and T2D, clinical evidences from more than one energetic biomarker are crucial. Current multiplexed systems present limited multiplicity capacities because they combine individual tests spatially separated from the others requiring complex and bulky instruments (e.g. HPLC), so they are difficult to operate out of the laboratory. Other described tests also cannot be adapted to monitor chronic disorders because they present at least one of the following critical limitations: (1) they are semi-quantitative (e.g. lateral flow test) so cannot perform the analyte monitoring to the required level of precision, (2) restricted to a single analyte which does not address the accepted criteria that an obesity management requires clinical evidence from multiple biomarkers and/or (3) cannot integrate the microfluidic processing required for blood analysis. To overcome current limitations, a novel multiplexed medical device is proposed here to enable for the very first time the fully control and management of chronic disorders as obesity and T2D. This will combine optics, electrochemistry, microfluidics and optoelectronics to monitor the most appropriate energy biomarkers (succinate as novel metabolite, in addition to lactate, ketones, pyruvate and glycaemia) in a friendly and decentralised way. No one has previously proposed a useful multiplexed approach as this, allowing the opportunity of the control of a particular energy biomarker such as succinate, which will facilitate current chronic disorders management. Thus, this novel cost-effective and portable multiplexed medical device, with unique and unprecedented attributes, will play a role key in the accurate management of chronic disorders.

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