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Drug Absorption in Geriatric Patients and Older People a training network innov...

Drug Absorption in Geriatric Patients and Older People a training network innovating drug development for the advanced age population The advanced age population (>65y) makes up ~20% of the total population in Europe, is the main carrier of chronic diseases and the major end-user group of medications. Yet, despite an ageing society, these end-users are entirely... see more

31/12/2024

UOA

3M€

Project Budget: 3M€

Project leader

ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINO... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo H2020 notifico la concesión del proyecto The day 2024-12-31

MSCA-ITN-2020: Innovative Training Networks Objective:The Innovative Training Networks (ITN) aim to train a new generation of creative, entrepre...

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Cerrada does 5 years

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

6 Participantes

UOA

729.05K€ | Leader

F. HoffmannLa Roche AG

281.28K€ | participant

BAYER AKTIENGESELLSCHAFT

252.79K€ | participant

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Project duration: 52 months Date Start: 2020-08-18
End date: 2024-12-31

Project leader

ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINO... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 3M€

participation deadline Sin fecha límite de participación.

Project description The advanced age population (>65y) makes up ~20% of the total population in Europe, is the main carrier of chronic diseases and the major end-user group of medications. Yet, despite an ageing society, these end-users are entirely disregarded in the drug development process, which considers only healthy adults aged 18-55. Effective absorption of oral drugs, which remain the preferred form of administration, relies on a sound knowledge of the physiological alterations associated with ageing and of the characteristics of the gastrointestinal (GI) tract in older subjects. Nonetheless, both the knowledge and the experts in this area are lacking. The AGePOP European Training Network (ETN) will boost Europe’s innovation capacity and leadership in oral drug development. Its multisectoral approach will train 11 Early Stage Researchers (ESRs) to become the future experts in drug development for the advanced age population, shedding a much needed light on the needs of our ageing society. With an open science philosophy and a multidisciplinary strategy, the ESRs will collect the first ever dataset of physiological characteristics of the GI tract of older people and geriatric patients, developing novel in vitro and in silico tools, e.g. a mobile test kit to evaluate gastric emptying kinetics and an absorption risk calculator to predict adverse effects from altered pharmacokinetics. Complementary training in transferable, business and wider horizon skills will equip the ESRs with an all-rounded skillset. AGePOP is a network of 6 Beneficiaries and 7 Partner Organisations from 5 European countries. Its 3 academic partners with research excellence in oral drug products synergise with renowned clinicians and researchers from 8 leading pharma companies and 1 SME specialised in ETN training. Building on long-standing collaborations, the consortium will provide 11 ESRs with a unique Europe-wide learning experience, preparing them to lead their future careers with confidence and success.

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