DISCO
Financiado
DNA-based Infrastructure for Storage and Computation
Throughout evolution, Biology has found an almost-perfect molecule to pass information down through the millennia. Whether for a simple bacterium or the largest whale, DNA achieves high information density while permitting cellul...
Throughout evolution, Biology has found an almost-perfect molecule to pass information down through the millennia. Whether for a simple bacterium or the largest whale, DNA achieves high information density while permitting cellular machinery rapid random-access retrieval to decode everything from a single protein to the development of an entire human brain. Humanity's rapidly-growing data storage and computing needs make it is tempting to exploit optimised biological molecules and processes, but biology is messy, poorly-understood and much more specialised for life than it is for our needs -- we propose to use DNA for storage together with a rationally designed, well-characterised and robust molecular computing architecture.
The DISCO project will address the challenge of engineering a programmable and robust DNA storage and computing platform. DISCO combines powerful molecular-algorithmic ideas from DNA computing with notions of thermodynamic stability from DNA nanostructures, to provide an expressive and robust system design. The project proposes the use of long DNA scaffold strands, upon which hundreds of smaller strands bind to store data, which can be later read, erased, rewritten and computed upon. DISCO begins with the aim of trialing a small, but thoroughly characterised and modelled prototype, that facilitates storage and computation on 10 bits. Then, DISCO will scale-up the system to hundreds of bits by leveraging recent technological advances to enable high-throughput techniques at both the experimental and data-readout stages. Finally, DISCO will be extended to two-dimensional DNA origami structures, each carrying about a hundred bits, but with millions of structures in the same test tube, exhibiting DNA storage and computation in a distributed system at a massively parallel scale.
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Duración del proyecto: 63 meses
Fecha Inicio: 2023-06-21
Fecha Fin: 2028-09-30
Fecha Fin: 2028-09-30
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-06-21
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
Presupuesto
El presupuesto total del proyecto asciende a
4M€
Líder del proyecto
NATIONAL UNIVERSITY OF IRELAND MAYNOOTH
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5
180.00K€ |
Participante
292.50K€ |
Participante