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IBDIMAGE

Financiado

Disruptive fluorescent technologies for inflammatory bowel diseases

Inflammatory bowel diseases (IBD) are chronic immune-mediated disorders causing inflammation of the gastrointestinal tract, which affect around 3 million patients in the EU. Current monitoring of IBD is mainly performed in the for... ver más

31/10/2022

UEDIN

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

THE UNIVERSITY OF EDINBURGH No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 2 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2022-10-31

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

ERC-2020-POC: Call for proposals for ERC Proof of Concept Grant

I+D

Cerrada hace 4 años

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2 Participantes

UEDIN

150.00K€ | Lider

BIAL INDUSTRIAL FARMACÉUTICA...

273.08K€ | Participante

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Últimas noticias

29-11-2024: IDAE En las últimas 48 horas el Organismo IDAE ha otorgado 4 concesiones

29-11-2024: ECE En las últimas 48 horas el Organismo ECE ha otorgado 2 concesiones

29-11-2024: CMVAMADRID En las últimas 48 horas el Organismo CMVAMADRID ha otorgado 37 concesiones

Duración del proyecto: 27 meses Fecha Inicio: 2020-07-31
Fecha Fin: 2022-10-31

Líder del proyecto

THE UNIVERSITY OF EDINBURGH

TRL 4-5

Presupuesto del proyecto 150K€

Descripción del proyecto Inflammatory bowel diseases (IBD) are chronic immune-mediated disorders causing inflammation of the gastrointestinal tract, which affect around 3 million patients in the EU. Current monitoring of IBD is mainly performed in the form of colonoscopies, biopsies or tests which are invasive or cannot specifically report on IBD activity. There is a need for new technologies that can rapidly measure activity biomarkers of IBD and enable the monitoring of disease progression and response to therapy accurately. This unmet patient need is what drives the development of this ERC PoC project. The ERC CoG DYNAFLUORS (Dynamic Activatable Fluorophores) project was funded to develop the first chemical toolbox for imaging the activity of immune cells in real time. In IBD, the activity of immune cells are important indicators of the disease state and can be used to assess how patients respond to therapy. DYNAFLUORS measure real-time immune cell activity; hence they are optimal tools to monitor disease progression in IBD patients facilitating a more accurate and personalised therapeutic approach. Based on our promising results in the ERC CoG, we aim to develop DYNAFLUORS into a new fluorescent technology for imaging IBD activity which will lead to: 1) new tools for IBD research and drug discovery in collaboration with companies covering the global fluorescent reagent market as well as Pharma, and 2) point-of-care technologies for clinical diagnostics in IBD patients. Funding from the ERC PoC will allow us to commercialise fluorescent reagents for research, in vitro diagnostics and drug discovery as well as to establish the foundations for new translational technologies to measure IBD activity in patients. This project will be guided by input from existing and new industrial and clinical partners and will create numerous opportunities for accelerating the research, diagnosis and treatment of IBD.

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