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ASTROTECH

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Disruptive materials technologies approaches to unravel the role of Astrocyt...

Disruptive materials technologies approaches to unravel the role of Astrocytes in brain function and dysfunction towards to Glial interfaces The past four decades demonstrated that non-neuronal cells, called astrocytesare emerging as crucial players for brain function & dysfunction. A major obstacle of previous and current initiatives on Neurotechnologiesis a lack of f... see more

30/04/2025

CNR

4M€

Project Budget: 4M€

Project leader

CONSIGLIO NAZIONALE DELLE RICERCHE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo H2020 notifico la concesión del proyecto The day 2025-04-30

MSCA-ITN-2020: Innovative Training Networks Objective:The Innovative Training Networks (ITN) aim to train a new generation of creative, entrepre...

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Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

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11 Participantes

CNR

784.50K€ | Leader

IIT

261.50K€ | participant

AMU

549.60K€ | participant

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Project duration: 55 months Date Start: 2020-09-04
End date: 2025-04-30

Project leader

CONSIGLIO NAZIONALE DELLE RICERCHE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 4M€

participation deadline Sin fecha límite de participación.

Project description The past four decades demonstrated that non-neuronal cells, called astrocytesare emerging as crucial players for brain function & dysfunction. A major obstacle of previous and current initiatives on Neurotechnologiesis a lack of focus on astrocytesand most of the tools used to probe and sense astrocytes are derived from those developed to study neurons. ASTROTECH will create and develop the field of Glial Engineering, to provide a consistent range of tools to record, study, and manipulate astrocytes in the healthy and diseased brain. ASTROTECH will train 15 Early Stage Researchers (ESRs) on research, training and complimentary skills aiming at: engineering biomaterials and nanostructured interfaces to provide in vivo-like in vitro models for controlled & reliable studies of astrocytes in vitro; fabrication and characterization of nanostructured devices for stimulation, recording and biosensing of astrocytes; optogenetics tools, optoelectronic device &photonic methods for precice and cell selective stimulation of astrocytes; computationalapproaches to describe and predict neuron-astrocytes interactions.The training on state-of-the-art biomaterials interfaces, electronic, photonic devices will be combined with in depth knowledge on optogenetics, neuroscience, glial physiology and biology and computational methodsto validate the developed tools in vitro, ex vivo, in silico & in pathological models of glioma, ischemia, epilepsy and depression.The ASTROTECH network combines 11 beneficiaries and 14 partners belonging to 9 European and Non-EU countries Academia, Public Research Centersand industrial labs, that combines interdisciplinary, intersectoral and soft skills knowledges where the private sector is highly representedand covers every step from benchside to bedside of the value chain. ASTROTECH Glial Engineeringto provide a more complete understanding of brain health and disorders.

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