Innovating Works

Bcl-Inhib

Financiado
Discovery of Bcl 3 inhibitors as Potential Chemopreventive Agent for skin cancer
Melanoma is one of the fastest growing cancers worldwide, especially in regions with a high number of Caucasians such as Europe. Currently, 100,000 diagnoses and 5,000 deaths from melanoma are registered in Europe every year. This... Melanoma is one of the fastest growing cancers worldwide, especially in regions with a high number of Caucasians such as Europe. Currently, 100,000 diagnoses and 5,000 deaths from melanoma are registered in Europe every year. This increase in melanoma incidence is a serious health problem and poses an economic as well as societal concern. The survival in patients with malignant melanoma is very poor with a five year survival rate of about 10%. Indeed, the current clinical therapies against malignant and metastatic melanoma have a relatively low efficacy and are associated with significant adverse events. Therefore there is an urgent need for development of novel drugs that can cure or prolong the survival of these patients. Molecular targeted therapy by using a drug that reduces the growth and spread of cancer cells via inhibition of a specific protein is a foundation stone of precision medicine and treatment. We have identified a lead molecule that inhibits proliferation and metastasis of human malignant melanoma cells. The present proof-of-concept proposal aims at lead optimization, preclinical verification, IPR positioning, market assessment, and other commercial activities including go to market strategy and dialogue with potential collaborators. This will make a unique medical and commercial opportunity to develop a highly specific drug against a disease in urgent need of new treatment options. ver más
30/04/2017
LUNDS UNIVERSITET
150K€
Duración del proyecto: 18 meses Fecha Inicio: 2015-10-29
Fecha Fin: 2017-04-30

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2017-04-30
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-PoC-2015: ERC Proof of Concept Grant
Cerrada hace 9 años
Presupuesto El presupuesto total del proyecto asciende a 150K€
Líder del proyecto
LUNDS UNIVERSITET No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5