Innovating Works

InstantScope

Financiado
Development of high resolution high throughput microscopy
Current 3D microscopy methods are limited in speed due to the need to scan the sample in the optical axis. Multifocus microscopy - or MFM- is a method that allows for the instant acquisition of a 3D volume without scanning, thus i... Current 3D microscopy methods are limited in speed due to the need to scan the sample in the optical axis. Multifocus microscopy - or MFM- is a method that allows for the instant acquisition of a 3D volume without scanning, thus increasing acquisition speed by a factor of 10-100. MFM based on diffractive optics allows for easy optimization of the total volume acquired and the sampling rate. In our ERC-StG project, we developed an important expertise in the design and construction of diffractive elements key to MFM and invented a novel super-resolution imaging method based on this technology (patent pending). In this project, we propose to further improve the conception and fabrication methods of MFM’s diffractive elements to considerably improve acquisition speed and resolution. In addition, we will employ these technologies in conjunction with valve-based microfluidics to develop and validate a microscopy-based high-resolution, high-throughput cell profiler (Hi2M). Hi2M will allow for the 3D acquisition of complete cell volumes in <10 ms, enabling the high-resolution, multi-color imaging of millions of cells/hour without the need for cell adhesion. Because of these important advantages over existing microscopies, we anticipate that the technologies developed in InstantScope should have a large impact in many fields of cell biology. ver más
31/08/2018
INSERM
150K€
Duración del proyecto: 18 meses Fecha Inicio: 2017-02-24
Fecha Fin: 2018-08-31

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2018-08-31
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-PoC-2016: ERC-Proof of Concept-2016
Cerrada hace 8 años
Presupuesto El presupuesto total del proyecto asciende a 150K€
Líder del proyecto
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHER... No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5