REPLANT
Financiado
Development of a revised plant synthetic biology toolkit to advance crop improve...
Agronomy faces significant global challenges such as coping with climate change, a need for more sustainable practices, and an increasing demand for more food of higher quality due to a growing population. Addressing them will req...
Agronomy faces significant global challenges such as coping with climate change, a need for more sustainable practices, and an increasing demand for more food of higher quality due to a growing population. Addressing them will require the adoption of transformative innovations, such as the genetic technologies that underlie Plant Synthetic Biology (SynBio). Plant SynBio, through transgenesis and more recently gene editing, allows us to proactively alter plant DNA to modify their characteristics and address the aforementioned challenges. In addition, plant SynBio can enhance the production of high-value, or new compounds in plants by molecular farming.
SynBio requires the generation of complex DNA constructs that comprise several transcriptional units, facilitated by the development of modular cloning toolkits and the Phytobrick Standard Syntax, a recent agreement of the plant SynBio community that systematized the sequence requirements for cloning.
The aim of REPLANT is to generate a new plant SynBio toolkit based on the Phytobrick architecture that includes the latest developments in protein production and gene editing techniques. The advantages provided by the REPLANT will be demonstrated by two proof-of-concept experiments with biotechnological applications: enhancing the production of SARS-CoV2 recombinant antibodies in plant leaves, and modification of tomato plant architecture in variants of commercial interest. This toolkit, alongside its dissemination approaches will allow a faster advancement of plant SynBio, accelerating the development of improved crops to help solve the global challenges of sustainability and food security.
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Duración del proyecto: 30 meses
Fecha Inicio: 2022-05-17
Fecha Fin: 2024-11-30
Fecha Fin: 2024-11-30
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-05-17
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
HORIZON-MSCA-2021-PF-01-01:
MSCA Postdoctoral Fellowships 2021
Cerrada
hace 3 años
Presupuesto
El presupuesto total del proyecto asciende a
207K€
Líder del proyecto
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGA...
Investigaciones agrarias
Perfil tecnológico
TRL
2-3
552M
Perfil tecnológico
TRL
2-3
552M