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Colodetect

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Development of a novel blood based diagnostic test for colorectal cancer

A recent epidemiology of colorectal cancer (CRC) report demonstrated a significant CRC burden in European countries, which is still associated with very high mortality rates. The overall objective of the project is the development... ver más

31/03/2019

PROTEIN ALTERNATIV...

2M€

Presupuesto del proyecto: 2M€

Líder del proyecto

PROTEIN ALTERNATIVES La investigacion, produccion y comercializacion de reactivos biologicos de interes para la investigacion cientifica, el diagnostico y la ter...

TRL 3-4 | 260K€

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2019-03-31

PHC-12-2014: Clinical research for the validatio...

I+D

Cerrada hace 10 años

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

PROTEIN ALTERNATIVES

2.31M€ | Lider

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Duración del proyecto: 42 meses Fecha Inicio: 2015-09-09
Fecha Fin: 2019-03-31

Líder del proyecto

PROTEIN ALTERNATIVES La investigacion, produccion y comercializacion de reactivos biologicos de interes para la investigacion cientifica, el diagnostico y la ter...

TRL 3-4 | 260K€

Presupuesto del proyecto 2M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto A recent epidemiology of colorectal cancer (CRC) report demonstrated a significant CRC burden in European countries, which is still associated with very high mortality rates. The overall objective of the project is the development and commercialization of a test for the early detection of CRC based on the detection and measurement of cancer-specific autoantibodies present in blood of patients. The outlined test will detect simultaneously the presence in serum/plasma samples from CRC patients of specific autoantibodies (biomarkers) against a reduced number of tumor antigens (8-10). To reach this objective, several technological challenges have to be overcome, like to improve the sensitivity and detection limit in the early stages of CRC avoiding the obvious limitations provided by the invasive detection techniques extensively used, as the colonoscopy, and offering additional advantages compared to traditional CRC diagnostic methods, such the simplicity in applications, detection, accuracy and a reduced cost. The assay for the detection of CRC will be established and validated with clinical samples and tested for their marketability, to finally overtake the regulatory process to obtain the CE marking. The results obtained in this project will have extensive impact and benefits for European population at risk, since early detection programs are essential to decrease mortality around 30-35% and drastically reduce the treatment costs of people affected by the pathology, assuring the sustainability of the European healthcare systems and others in the world. The main objective of this project is to obtain a colorectal cancer diagnostic kit clinically validated and regulatory approved as an in vitro diagnostic product (IVD), and as well, to penetrate in the CRC diagnostic market allowing ProAlt to reach a competitive position by improving its competitiveness.

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