Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

MUCOSITIS PLATFORM

Financiado

Cerrado

Development of a multidisciplinary platform for the screening of new preventive...

Development of a multidisciplinary platform for the screening of new preventive and therapeutic strategies against oral mucositis Both from the European Centre for the Validation of Alternative Methods and worldwide, there is a general call for the reduction, refinement or replacement of the use of laboratory animals. However, while in vivo animal models of... ver más

31/01/2016

UGent

279K€

Presupuesto del proyecto: 279K€

Líder del proyecto

UNIVERSITEIT GENT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2016-01-31 No tenemos la información de la convocatoria

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

UGent

0.00€ | Lider

Proyectos interesantes

ONCORED

Medical Technol...

Medical Devices

71K€ Cerrado

PreBiomicsPMT

Medical Technol...

Data Science

2M€ Cerrado

Murnia

Medical Technol...

Medical Devices

75K€ Cerrado

POC-TDM

Medical Technol...

Data Science

158K€ Cerrado

CD-ResOMics

Medical Technol...

Health Informat...

173K€ Cerrado

RTC-2014-2472-1

Medical Technol...

Data Science

140K€ Cerrado

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Líder del proyecto

UNIVERSITEIT GENT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 279K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Both from the European Centre for the Validation of Alternative Methods and worldwide, there is a general call for the reduction, refinement or replacement of the use of laboratory animals. However, while in vivo animal models of chemotherapy and radiotherapy-induced oral mucositis have been successfully established, alternative methods such as in vitro tools for mucositis are still missing. Oral mucositis is a severe side effect of both chemo- and radiotherapy and is the cause of inflammation of the mucosa of the mouth. Symptoms of mucositis vary from pain and discomfort to an inability to tolerate food or fluids. Apart from being treatment limiting, also the quality-of-life of patients and the economic costs of supportive therapies are of significant concern. Given that hundreds of thousands of patients worldwide are affected by mucositis annually, a significant need for effective therapy exists. However, there is no actual treatment. Therefore, new tools are urgently required to allow a rapid and high-throughput screening of new-generation anti-mucositis drugs and strategies. The objectives of this project can be summarized as follows: 1. Generation and critical evaluation of an innovative high-throughput in vitro model of oral mucositis; 2. In vivo validation of the in vitro model using established animal models of chemo/radiotherapy-induced mucositis; 3. Exploration of the in vitro and in vivo tools to identify new biomarkers and risk factors of mucositis in order to anticipate animal and human chemo/radiotoxicity and to enhance anti-mucositis drug screening. The set up of the platform requires an international and a multidisciplinary approach, involving prominent experts in the mucositis, cancer biology and medical microbiology field and a strong interaction with the clinical oncology society. In return, the platform generates an opportunity to achieve a substantial reduction of animal experiments in mucositis risk assessments.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores