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DEEPER

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DEEP BRAIN PHOTONIC TOOLS FOR CELL TYPE SPECIFIC TARGETING OF NEURAL DISEASES

While brain disorders have different etiology and stem from distinct molecular and cellular dysfunctions, due to limitation in current technology they all share an incomplete understanding of the anatomical and functional alterati... see more

30/04/2025

IIT

6M€

Project Budget: 6M€

Project leader

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

Ver 13 Participantes

Financing granted El organismo H2020 notifico la concesión del proyecto The day 2025-04-30

ICT-36-2020: Disruptive photonics technologies Specific Challenge:The challenge is the development of advanced photonics technologies which have th...

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

13 Participantes

IIT

1.24M€ | Leader

SECURE SOLUTIONS

193.06K€ | participant

UNIVERSITY OF STRATHCLYDE

699.92K€ | participant

INSTITUTE OF SCIENTIFIC INST...

402.50K€ | participant

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Project duration: 52 months Date Start: 2020-12-15
End date: 2025-04-30

Project leader

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 6M€

participation deadline Sin fecha límite de participación.

Project description While brain disorders have different etiology and stem from distinct molecular and cellular dysfunctions, due to limitation in current technology they all share an incomplete understanding of the anatomical and functional alterations occurring in hard-to-access deep regions of the brain. DEEPER aims at tackling this fundamental challenge by developing an entire new class of photonic tools for imaging and manipulating neuronal activity in the deep brain with unprecedented penetration depth, resolution, sensitivity, specificity and depth of focus. Technology development in DEEPER will be driven by medical expertise and market requirements and it will be organized in three pillars focusing on: i) novel high-efficiency molecular sensors and actuators; ii) minimally invasive probes for monitoring and perturbing large populations of cells; iii) next generation multiphoton microscopes and microendoscopes. In a fourth pillar, this technological platform will enable a number of clinically relevant experiments which will contribute to reveal the molecular and cellular dysfunctions underlying the pathogenesis of specific neurological (addiction, chronic pain, Alzheimer’s disease) and psychiatric disorders (depression, schizophrenia, and autism). By shedding new light on the pathogenesis of disorders, which dramatically touch the lives of millions, DEEPER has the potential to profoundly impact our society. Moreover, in DEEPER technologists, neuroscientists, clinical and pre-clinical experts will bring the results from laboratory research to market supported by the SMEs in the consortium and by the companies and experts in the advisory board. This will make the translation and exploitation of the DEEPER technologies fast and effective, building a value chain with strong translational appeal that will strengthen Europe’s industrial position in the biophotonics market for optical neural interfaces, microscopy, and microendoscopy.

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