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COBIOPHAD

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COMPACT BIOPHOTONIC PLATFORM FOR DRUG ALLERGY DIAGNOSIS

Drug hypersensitivity to antibiotics, mainly Beta-lactams (BLCs) affects more than 2.5 million European citizens. Moreover, preventable adverse drug reactions are estimated in additional hospitalization costs of 1750-4500 €/patien... see more

31/07/2019

UPV

4M€

Project Budget: 4M€

Project leader

UNIVERSITAT POLITÈCNICA DE VALÈNCIA No se ha especificado una descripción o un objeto social para esta compañía.

total researchers 713

PARTICIPATION DEPralty Sin fecha límite de participación.

Ver 13 Participantes

Financing granted El organismo H2020 notifico la concesión del proyecto The day 2019-07-31

ICT-28-2015: Cross-cutting ICT KETs Scope:Specific Challenge: Europe is facing fierce global competition to maintain its technological l...

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

13 Participantes

UPV

1.03M€ | Leader

AB AZUCARERA IBERIA

543.92K€ | participant

CENTRE HOSPITALIER UNIVERSIT...

451.93K€ | participant

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Project duration: 43 months Date Start: 2015-12-09
End date: 2019-07-31

Project leader

UNIVERSITAT POLITÈCNICA DE VALÈNCIA No se ha especificado una descripción o un objeto social para esta compañía.

total researchers 713

Project Budget 4M€

participation deadline Sin fecha límite de participación.

Project description Drug hypersensitivity to antibiotics, mainly Beta-lactams (BLCs) affects more than 2.5 million European citizens. Moreover, preventable adverse drug reactions are estimated in additional hospitalization costs of 1750-4500 €/patient. Currently, the allergy diagnosis is mainly based on the information given by invasive, single, and risky in vivo assays. In daily practice, few in vitro diagnostic methods are available and only used at the tertiary health services. These tests also lack of sensitivity (>0.35 kUA/L) and selectivity (<98%), resulting in an inaccurate diagnosis, analyze few drugs allergens (5), are time consuming (60-180 min), and expensive (30 €/allergen). COBIOPHAD aims the development of an innovative in vitro diagnostic (IVD) device for diagnosis of IgE-mediated drug allergies by building an integrated biophotonic system based on compact disc technology. For that, key enabling technologies will be integrated in order to achieve high sensitive (<0.1 kUA/L), selective (>98%), multiplexed (10 BLCs), rapid (30 min), and low-cost (2.4 €/allergen) drug allergy test. The solution involves an advanced approach to the diagnosis and management of drug allergy with the aim to ameliorate patient safety. The consortium comprises multidisciplinary knowledge on optics, electronics, advanced materials, biotechnology, smart microstructures, microfluidics, surface/organic chemistry, allergy, manufacturing systems, and telecom networking. Also, the key industrial actors, present in the consortium, will contribute to the manufacturing and placing the product on the IVD market.

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