COBIOPHAD
Financiado
COMPACT BIOPHOTONIC PLATFORM FOR DRUG ALLERGY DIAGNOSIS
Drug hypersensitivity to antibiotics, mainly Beta-lactams (BLCs) affects more than 2.5 million European citizens. Moreover, preventable adverse drug reactions are estimated in additional hospitalization costs of 1750-4500 €/patien...
Drug hypersensitivity to antibiotics, mainly Beta-lactams (BLCs) affects more than 2.5 million European citizens. Moreover, preventable adverse drug reactions are estimated in additional hospitalization costs of 1750-4500 €/patient. Currently, the allergy diagnosis is mainly based on the information given by invasive, single, and risky in vivo assays. In daily practice, few in vitro diagnostic methods are available and only used at the tertiary health services. These tests also lack of sensitivity (>0.35 kUA/L) and selectivity (<98%), resulting in an inaccurate diagnosis, analyze few drugs allergens (5), are time consuming (60-180 min), and expensive (30 €/allergen).
COBIOPHAD aims the development of an innovative in vitro diagnostic (IVD) device for diagnosis of IgE-mediated drug allergies by building an integrated biophotonic system based on compact disc technology. For that, key enabling technologies will be integrated in order to achieve high sensitive (<0.1 kUA/L), selective (>98%), multiplexed (10 BLCs), rapid (30 min), and low-cost (2.4 €/allergen) drug allergy test. The solution involves an advanced approach to the diagnosis and management of drug allergy with the aim to ameliorate patient safety.
The consortium comprises multidisciplinary knowledge on optics, electronics, advanced materials, biotechnology, smart microstructures, microfluidics, surface/organic chemistry, allergy, manufacturing systems, and telecom networking. Also, the key industrial actors, present in the consortium, will contribute to the manufacturing and placing the product on the IVD market.
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Duración del proyecto: 43 meses
Fecha Inicio: 2015-12-09
Fecha Fin: 2019-07-31
Fecha Fin: 2019-07-31
Línea de financiación: concedida
El organismo H2020 notifico la concesión del proyecto el día 2019-07-31
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
ICT-28-2015:
Cross-cutting ICT KETs
Cerrada
hace 9 años
Presupuesto
El presupuesto total del proyecto asciende a
4M€
Líder del proyecto
UNIVERSITAT POLITÈCNICA DE VALÈNCIA
Es la prestacion del servicio publico de la educacion superior mediante la docencia, el estudio y la investigacion. son funciones de la univ...
Total investigadores
683
Total investigadores
683
451.93K€ |
Participante